Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-

Base Information

Chemical Name:Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-
CAS No.:22248-13-1
Molecular Formula:C10H12O4
Molecular Weight:196.203
Hs Code.:
ChEMBL ID:CHEMBL3955298
DSSTox Substance ID:DTXSID00496828
Wikidata:Q82345959

Synonyms:Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-;22248-13-1;1-(6-hydroxy-2,3-dimethoxyphenyl)ethanone;1-(6-Hydroxy-2,3-dimethoxyphenyl)ethan-1-one;SCHEMBL3302610;CHEMBL3955298;DTXSID00496828;1-(6-hydroxy-2,3-dimethoxy-phenyl)-ethanone

Suppliers and Price of Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-

Chemical Property:

Melting Point:162–163°C
PSA：55.76000
LogP:1.61200
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:196.07355886
Heavy Atom Count:14
Complexity:204

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=C(C=CC(=C1OC)OC)O

Technology Process of Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)-

There total 5 articles about Ethanone, 1-(6-hydroxy-2,3-dimethoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 33539-20-7
6-methoxy-2,5-dihydroxyacetophenone

: 77-78-1
dimethyl sulfate

: 22248-13-1
1-(6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 168h;
DOI:10.1021/jm060915+

Reference yield:

: isofraxetin 6-O-β-D-glucopyranoside

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 50656-75-2
5,6-dihydroxy-7-methoxycoumarin

: 55396-45-7
2-nonyl-4-hydroxyquinoline N-oxide

: 486-21-5
isofraxidin

: 726-18-1
4,4'-dianisylmethane

: 30567-87-4
2,4'-dimethoxydiphenylmethane

: 22248-13-1
1-(6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

: 6935-99-5
2,4-bis(methoxycarbonylamino)toluene

: 20913-18-2
toluene-2,6-bis(methyl) carbamate

: 8'-dehydroxymethyl cleomiscosin A

: 103-81-1
Benzeneacetamide

: 61281-37-6,66211-88-9,69176-52-9,82467-51-4,82467-52-5,82467-53-6,82467-54-7,64121-95-5
gomisin N

: 66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6
uracil

: (+)-isoschizandrin

: 6-methoxy-5′′-demethoxydaphneticin

Guidance literature:: With Angelica sinensis (Oliv_.) Diels callus; In methanol; for 168h;
DOI:10.1016/j.bmcl.2016.11.069

Reference yield:

: 703-23-1
2'-hydroxy-6'-methoxyacetophenone

: 22248-13-1
1-(6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / aq. NaOH; K₂S₂O₈ / 168 h / 20 °C

2: 89 percent / K₂CO₃ / acetone / 168 h / 20 °C

With sodium hydroxide; dipotassium peroxodisulfate; potassium carbonate; In acetone; 1: Elbs oxidation;
DOI:10.1021/jm060915+