1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one

Base Information

Chemical Name:1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one
CAS No.:223137-71-1
Molecular Formula:C19H20Br2O3
Molecular Weight:456.174
Hs Code.:
DSSTox Substance ID:DTXSID70469201
Wikidata:Q82296814

Synonyms:1,5-bis(2-bromo-5-methoxyphenyl)pentan-3-one;223137-71-1;3-Pentanone, 1,5-bis(2-bromo-5-methoxyphenyl)-;SCHEMBL13647141;DTXSID70469201

Suppliers and Price of 1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:8
Exact Mass:455.97587
Heavy Atom Count:24
Complexity:357

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)Br)CCC(=O)CCC2=C(C=CC(=C2)OC)Br

Technology Process of 1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one

There total 4 articles about 1,5-Bis(2-bromo-5-methoxyphenyl)pentan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 223137-71-1
1,5-bis-(2-bromo-5-methoxyphenyl)-3-pentanone

Guidance literature:: Multi-step reaction with 3 steps

1: 62 percent / aq. NaOH / ethanol / 2 h / Ambient temperature

2: H₂ / Raney Ni / acetone / 24 h / 760 Torr / Ambient temperature

3: Br₂, pyridine / CH₂Cl₂ / 4 h / Ambient temperature

With pyridine; sodium hydroxide; hydrogen; bromine; nickel; In ethanol; dichloromethane; acetone;
DOI:10.1016/S0957-4166(98)00481-9

Reference yield:

: 458533-66-9
(1E,4E)-1,5-bis(3-methoxyphenyl)penta-1,4-dien-3-one

: 223137-71-1
1,5-bis-(2-bromo-5-methoxyphenyl)-3-pentanone

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Raney Ni / acetone / 24 h / 760 Torr / Ambient temperature

2: Br₂, pyridine / CH₂Cl₂ / 4 h / Ambient temperature

With pyridine; hydrogen; bromine; nickel; In dichloromethane; acetone;
DOI:10.1016/S0957-4166(98)00481-9

Reference yield:

: 591-31-1
3-methoxy-benzaldehyde

: 223137-71-1
1,5-bis-(2-bromo-5-methoxyphenyl)-3-pentanone

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / diethyl ether; water / 4 h / 20 °C

2: hydrogen / acetone / 24 h / 20 °C / 760.05 Torr

3: sodium bromide; dihydrogen peroxide / acetic acid / 20 °C

With hydrogen; dihydrogen peroxide; sodium bromide; sodium hydroxide; In diethyl ether; water; acetic acid; acetone;
DOI:10.1016/j.catcom.2016.04.006