4-Hydroxydecanoic acid

Base Information

• Chemical Name: 4-Hydroxydecanoic acid
• CAS No.: 17369-51-6
• Molecular Formula: C₁₀H₂₀O₃
• Molecular Weight: 188.267
• Hs Code.: 2918199090
• DSSTox Substance ID: DTXSID10938421
• Nikkaji Number: J262.020K
• Metabolomics Workbench ID: 1307
• Mol file: 17369-51-6.mol

Synonyms:4-hydroxydecanoic acid

Chemical Property of 4-Hydroxydecanoic acid

Chemical Property:

• Vapor Pressure: 1.01E-05mmHg at 25°C
• Boiling Point: 332.9°Cat760mmHg
• Flash Point: 169.4°C
• PSA: 57.53000
• Density: 1.011g/cm³
• LogP: 2.18250
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 8
• Exact Mass: 188.14124450
• Heavy Atom Count: 13
• Complexity: 134

Purity/Quality:

99% ^*data from raw suppliers

4-HYDROXY DECANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCC(CCC(=O)O)O

Technology Process of 4-Hydroxydecanoic acid

There total 11 articles about 4-Hydroxydecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

5-hexyldihydro-2(3H)-furanone (706-14-9,2825-92-5) → 4-hydroxydecanoic acid (17369-51-6,30100-79-9)

Guidance literature:

With potassium hydroxide; In ethanol; at 25 ℃; for 1h;

Reference yield: 43.0%

R-12-hydroxyoctadecanoic acid (106-14-9,18417-00-0,36377-33-0,5762-36-7,78642-86-1,8039-23-4,27924-99-8,860114-96-1) → 5-hexyldihydro-2(3H)-furanone (706-14-9,2825-92-5) + 4-hydroxydecanoic acid (17369-51-6,30100-79-9) + 4-oxodecanoic acid (4144-54-1) + 5-n-hexyl-tetrahydrofuran-2-acetic acid

Guidance literature:

With ammonium sulfate; disodium hydrogenphosphate; potassium dihydrogenphosphate; calcium chloride; In ethanol; water; at 25 ℃; for 60h; Further byproducts given; Bacillus lentus NRRL B-14864, pH=7.2;

DOI:10.1007/BF02541090

Reference yield: 5.0%

R-12-hydroxyoctadecanoic acid (106-14-9,18417-00-0,36377-33-0,5762-36-7,78642-86-1,8039-23-4,27924-99-8,860114-96-1) → 5-hexyldihydro-2(3H)-furanone (706-14-9,2825-92-5) + 4-hydroxydecanoic acid (17369-51-6,30100-79-9) + 6-hydroxydodecanoic acid (35875-13-9) + 5-n-hexyl-tetrahydrofuran-2-acetic acid

Guidance literature:

With ammonium sulfate; disodium hydrogenphosphate; potassium dihydrogenphosphate; calcium chloride; In ethanol; water; at 25 ℃; for 60h; Further byproducts given; Bacillus lentus NRRL B-14864, pH=7.2;

DOI:10.1007/BF02541090

upstream raw materials:

5-hexyldihydro-2(3H)-furanone

R-12-hydroxyoctadecanoic acid

1-decanoic acid

Downstream raw materials:

(R)-5-Hexyl-dihydro-furan-2-one

(-)-(S)-γ-Decalactone