2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid

Base Information

Chemical Name:2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid
CAS No.:81265-63-6
Molecular Formula:C₁₆H₁₃ClN₂O₂
Molecular Weight:300.744
Hs Code.:
DSSTox Substance ID:DTXSID101001896
Nikkaji Number:J71.044J
Mol file:81265-63-6.mol

Synonyms:81265-63-6;M.G. 18827;2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid;Propionic acid, 2-(p-(6-chloro-2H-indazol-2-yl)phenyl)-;2-(p-(6-chloro-2h-indazol-2-yl)phenyl)Propanoic acid;DTXSID101001896;LS-124557;M.G.18827;2-[4-(6-Chloro-2H-indazol-2-yl)phenyl]propanoic acid

Suppliers and Price of 2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(P-(6-CHLORO-2H-INDAZOL-2-YL)PHENYL)PROPIONIC ACID 95.00%
5MG
$ 505.12

Total 3 raw suppliers

Chemical Property of 2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid

Chemical Property:

Vapor Pressure:2.44E-06mmHg at 25°C
Boiling Point:376.5°C at 760 mmHg
Flash Point:181.5°C
PSA：55.12000
Density:1.34g/cm³
LogP:3.86700
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:300.0665554
Heavy Atom Count:21
Complexity:385

Purity/Quality:: 2-(P-(6-CHLORO-2H-INDAZOL-2-YL)PHENYL)PROPIONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)N2C=C3C=CC(=CC3=N2)Cl)C(=O)O

Technology Process of 2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid

There total 3 articles about 2-(p-(6-Chloro-2H-indazol-2-yl)phenyl)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2-[4-(6-Chloro-indazol-2-yl)-phenyl]-propionic acid ethyl ester

: 81265-63-6
2-[4-(6-Chloro-indazol-2-yl)-phenyl]-propionic acid

Guidance literature:: With sodium hydroxide; In ethanol; water; for 12h; Heating;

Reference yield:

: 5551-11-1
4-Chloro-2-nitrobenzaldehyde

: 81265-63-6
2-[4-(6-Chloro-indazol-2-yl)-phenyl]-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) triethyl phosphite / 1.) methanol, 4 h, reflux; 2.) 8 h, 150 deg C

2: 75 percent / NaOH / ethanol; H₂O / 12 h / Heating

With sodium hydroxide; triethyl phosphite; In ethanol; water;

Reference yield:

: 26406-97-3
ethyl α-(3-chloro-4-aminophenyl)-propionate

: 81265-63-6
2-[4-(6-Chloro-indazol-2-yl)-phenyl]-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) triethyl phosphite / 1.) methanol, 4 h, reflux; 2.) 8 h, 150 deg C

2: 75 percent / NaOH / ethanol; H₂O / 12 h / Heating

With sodium hydroxide; triethyl phosphite; In ethanol; water;