Histidylproline zwitterion

Base Information

• Chemical Name: Histidylproline zwitterion
• CAS No.: 20930-58-9
• Molecular Formula: C11H16N4O3
• Molecular Weight: 252.273
• Mol file: 20930-58-9.mol

Synonyms:H-P zwitterion;His-Pro zwitterion;histidylproline zwitterion;L-His-L-Pro zwitterion;CHEBI:147379;(2S)-1-[(2S)-2-azaniumyl-3-(1H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxylate

Chemical Property of Histidylproline zwitterion

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 638.4°Cat760mmHg
• PKA: 3.04±0.20(Predicted)
• Flash Point: 339.9°C
• PSA: 112.31000
• Density: 1.432g/cm³
• LogP: -0.00670
• XLogP3: -3.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 252.12224039
• Heavy Atom Count: 18
• Complexity: 331

Purity/Quality:

99%+, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC(N(C1)C(=O)C(CC2=CN=CN2)[NH3+])C(=O)[O-]
• Isomeric SMILES: C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)[NH3+])C(=O)[O-]

Technology Process of Histidylproline zwitterion

There total 2 articles about Histidylproline zwitterion which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

His-Pro-Leu (142828-13-5) → L-leucine (61-90-5,21675-61-6,25248-98-0,70-45-1) + histidine-proline (20930-58-9)

Guidance literature:

at 37 ℃; for 0.166667h; 0.1 M Tris HCl buffer pH 8.0, X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR;

DOI:10.1271/bbb.56.704

Reference yield:

His-Pro-Tyr (136616-45-0) → L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) + histidine-proline (20930-58-9)

Guidance literature:

at 37 ℃; for 0.166667h; 0.1 M Tris HCl buffer pH 8.0, X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis subsp. cremoris nTR;

DOI:10.1271/bbb.56.704

upstream raw materials:

His-Pro-Tyr

His-Pro-Leu

Refernces