tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate

Base Information

Chemical Name:tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate
CAS No.:241499-44-5
Molecular Formula:C19H30N2O2
Molecular Weight:318.45400
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70377352
Wikidata:Q82166542
ChEMBL ID:CHEMBL1347310
Mol file:241499-44-5.mol

Synonyms:241499-44-5;tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate;tert-butyl 4-(4-propan-2-ylanilino)piperidine-1-carboxylate;tert-Butyl 4-((4-isopropylphenyl)amino)piperidine-1-carboxylate;MLS000721802;SCHEMBL7385548;CHEMBL1347310;DTXSID70377352;HMS2711O05;MFCD06659568;AKOS005070850;SMR000336945;CS-0362679;6Y-0211;J-524572;tert-Butyl4-((4-isopropylphenyl)amino)piperidine-1-carboxylate;tert-butyl 4-{[4-(propan-2-yl)phenyl]amino}piperidine-1-carboxylate

Suppliers and Price of tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate >95%
1g
$ 151.00

Matrix Scientific
tert-Butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate >95%
500mg
$ 118.00

Matrix Scientific
tert-Butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate >95%
5g
$ 346.00

Crysdot
tert-Butyl4-((4-isopropylphenyl)amino)piperidine-1-carboxylate 95+%
5g
$ 343.00

Chemenu
tert-Butyl4-((4-isopropylphenyl)amino)piperidine-1-carboxylate 95%
5g
$ 324.00

AK Scientific
tert-Butyl4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate
5g
$ 517.00

Total 3 raw suppliers

Chemical Property of tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate

Chemical Property:

Melting Point:99-100°
PSA：41.57000
LogP:4.63230
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:318.230728204
Heavy Atom Count:23
Complexity:373

Purity/Quality:

98%min ^*data from raw suppliers

tert-Butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=CC=C(C=C1)NC2CCN(CC2)C(=O)OC(C)(C)C

Technology Process of tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate

There total 5 articles about tert-butyl 4-(4-isopropylanilino)tetrahydro-1(2H)-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 99-88-7
4-Isopropylaniline

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 241499-44-5
N-(tert-butoxycarbonyl)-4-(4-isopropylanilino)piperidine

Guidance literature:: 4-Isopropylaniline; N-tert-butyloxycarbonylpiperidin-4-one; With 4 A molecular sieve; In dichloromethane; for 0.5h;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.bmc.2003.10.047

Reference yield:

: 4-(4-isopropyl-phenylimino)-piperidine-1-carboxylic acid tert-butyl ester

: 241499-44-5
N-(tert-butoxycarbonyl)-4-(4-isopropylanilino)piperidine

Guidance literature:: With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; for 18h;
DOI:10.1016/S0968-0896(00)00077-8

Reference yield:

: 99-88-7
4-Isopropylaniline

: 241499-44-5
N-(tert-butoxycarbonyl)-4-(4-isopropylanilino)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: CH₂Cl₂ / 0.5 h

2: NaBH(OAc)3 / CH₂Cl₂ / 18 h / 20 °C

With sodium tris(acetoxy)borohydride; In dichloromethane; 1: Condensation / 2: Reduction;
DOI:10.1016/S0968-0896(00)00077-8