6-4-Imdasd

Base Information

Chemical Name:6-4-Imdasd
CAS No.:102535-14-8
Molecular Formula:C₁₇H₂₂N₂O₂
Molecular Weight:286.374
Hs Code.:
DSSTox Substance ID:DTXSID90907690
ChEMBL ID:CHEMBL291141
Mol file:102535-14-8.mol

Synonyms:6-(4-indolylmethyl)-7-methyl-1,4-dioxa-7-azaspiro(4,5)decane;6-4-IMDASD

Suppliers and Price of 6-4-Imdasd

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6-4-Imdasd

Chemical Property:

Vapor Pressure:1.58E-08mmHg at 25°C
Boiling Point:456.7°Cat760mmHg
Flash Point:230°C
PSA：37.49000
Density:1.22g/cm³
LogP:2.48560
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:286.168127949
Heavy Atom Count:21
Complexity:370

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC2(C1CC3=C4C=CNC4=CC=C3)OCCO2

Technology Process of 6-4-Imdasd

There total 6 articles about 6-4-Imdasd which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 102520-45-6
ethyl 6-<<4-(p-tolylsulfonyl)indolyl>methyl>-1,4-dioxa-7-azaspiro<4.5>decane-7-carboxylate

: 102535-14-8
6-(4-Indolylmethyl)-7-methyl-1,4-dioxa-7-azaspiro[4.5]decane

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 12h; Heating;
DOI:10.1021/jm00158a036

Reference yield:

: 61995-19-5
ethyl 3-Oxopiperidine-1-carboxylate

: 102535-14-8
6-(4-Indolylmethyl)-7-methyl-1,4-dioxa-7-azaspiro[4.5]decane

Guidance literature:: Multi-step reaction with 4 steps

1: benzene / 1 h / 25 °C

2: benzene; acetonitrile / Heating

3: 77 percent / TsOH*H₂O / benzene / 12 h / Heating

4: 76 percent / LiAlH₄ / tetrahydrofuran / 12 h / Heating

With lithium aluminium tetrahydride; toluene-4-sulfonic acid; In tetrahydrofuran; acetonitrile; benzene;
DOI:10.1021/jm00158a036

Reference yield:

: 50606-58-1
N-benzyl-3-piperidinone hydrochloride

: 102535-14-8
6-(4-Indolylmethyl)-7-methyl-1,4-dioxa-7-azaspiro[4.5]decane

Guidance literature:: Multi-step reaction with 5 steps

1: 72 percent / Et₃N / CHCl₃ / 1 h / 25 °C

2: benzene / 1 h / 25 °C

3: benzene; acetonitrile / Heating

4: 77 percent / TsOH*H₂O / benzene / 12 h / Heating

5: 76 percent / LiAlH₄ / tetrahydrofuran / 12 h / Heating

With lithium aluminium tetrahydride; toluene-4-sulfonic acid; triethylamine; In tetrahydrofuran; chloroform; acetonitrile; benzene;
DOI:10.1021/jm00158a036