Benzoic acid, 2-mercapto-, hydrazide

Base Information

Chemical Name:Benzoic acid, 2-mercapto-, hydrazide
CAS No.:24611-43-6
Molecular Formula:C7H8N2OS
Molecular Weight:168.219
Hs Code.:
Mol file:24611-43-6.mol

Synonyms:thiosalicylic acid hydrazide;2-mercaptobenzoylhydrazine;N-amino(2-sulfanylphenyl)formamide;thiosalicylhydrazide;2-mercaptobenzohydrazide;2-mercapto-benzoic acid hydrazide;

Suppliers and Price of Benzoic acid, 2-mercapto-, hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-MercaptobenzoicAcidHydrazide
2.5g
$ 1395.00

Total 8 raw suppliers

Chemical Property of Benzoic acid, 2-mercapto-, hydrazide

Chemical Property:

PSA：97.41000
LogP:1.85390

Purity/Quality:

99% ^*data from raw suppliers

2-MercaptobenzoicAcidHydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-Mercaptobenzoic Acid Hydrazide is an intermediate used in the synthesis of N,N’-Bis(2-mercaptobenzoyl)hydrazide (B481825), which is a selective inhibitor of HIV-1 integrase. Has no other effect on other retroviral targets, including reverse transcriptase, protease, and virus attachement, and exhibits no detectable activity against human topoisomerases I and II at concentrations that effectively inhibit integrase.

Technology Process of Benzoic acid, 2-mercapto-, hydrazide

There total 4 articles about Benzoic acid, 2-mercapto-, hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 4892-02-8
Methyl thiosalicylate

: 24611-43-6
2-mercaptobenzoic acid hydrazide

Guidance literature:: With hydrazine hydrate; In methanol; for 12h; Reflux;
DOI:10.1371/journal.pone.0108338

Reference yield: 68.0%

: 1677-25-4
2-mercaptobenzoyl chloride

: 24611-43-6
2-mercaptobenzoic acid hydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 80 ℃; for 4h;
DOI:10.1016/j.tetlet.2021.153606

Reference yield:

: 147-93-3
Thiosalicylic acid

: 24611-43-6
2-mercaptobenzoic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 6 h / Reflux

2: hydrazine hydrate / ethanol / 6 h / Reflux

With sulfuric acid; hydrazine hydrate; In ethanol;
DOI:10.1007/s00044-012-0107-x