(S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Base Information

Chemical Name:(S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid
CAS No.:83468-83-1
Molecular Formula:C19H25 N3 O5
Molecular Weight:375.425
Hs Code.:
DSSTox Substance ID:DTXSID80460002
Nikkaji Number:J1.324.556H
Wikidata:Q72448651

Synonyms:Boc-His(Bom)-OH;N(alpha)-tert-butyloxycarbonyl-N(pi)-benzyloxyhistidine

Suppliers and Price of (S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Iris Biotech GmbH
Boc-L-His(Bom)-OH
100 g
$ 1282.50

Iris Biotech GmbH
Boc-L-His(Bom)-OH
25 g
$ 472.50

Iris Biotech GmbH
Boc-L-His(Bom)-OH
5 g
$ 121.50

Crysdot
(S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoicacid 97%
25g
$ 396.00

Alichem
(S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoicacid
25g
$ 440.00

Alfa Aesar
N-Boc-1-benzyloxymethyl-L-histidine, 97%
5g
$ 150.00

Alfa Aesar
N-Boc-1-benzyloxymethyl-L-histidine, 97%
1g
$ 42.90

Alfa Aesar
N-Boc-1-benzyloxymethyl-L-histidine, 97%
250mg
$ 17.80

Total 13 raw suppliers

Chemical Property of (S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

Chemical Property:

Appearance/Colour:white - off-white powder
Vapor Pressure:5.11E-15mmHg at 25°C
Melting Point:142-150ºC
Boiling Point:595.3°C at 760 mmHg
Flash Point:313.8°C
PSA：102.68000
Density:1.21g/cm³
LogP:2.96870
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:10
Exact Mass:375.17942091
Heavy Atom Count:27
Complexity:488

Purity/Quality:

99% ^*data from raw suppliers

Boc-L-His(Bom)-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CN(C=N1)COCC2=CC=CC=C2)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CN(C=N1)COCC2=CC=CC=C2)C(=O)O

Technology Process of (S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid

There total 3 articles about (S)-3-(1-((Benzyloxy)methyl)-1H-imidazol-4-yl)-2-((tert-butoxycarbonyl)amino)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 83468-82-0
N(α)-t-butoxycarbonyl-N(τ)-benzyloxymethyl-L-histidine methyl ester

: 83468-83-1
N(α)-t-butoxycarbonyl-N(?)-benzyloxymethyl-L-histidine

Guidance literature:: With sodium hydroxide; In methanol; for 0.5h;

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 83468-83-1
N(α)-t-butoxycarbonyl-N(?)-benzyloxymethyl-L-histidine

Guidance literature:: Multi-step reaction with 2 steps

1: 19 percent / Et₃N / CH₂Cl₂

2: 73 percent / aq. NaOH / methanol / 0.5 h

With sodium hydroxide; triethylamine; In methanol; dichloromethane;

Reference yield:

: 2488-14-4
N-(tert-butoxycarbonyl)-L-histidine methyl ester

: 83468-83-1
N(α)-t-butoxycarbonyl-N(?)-benzyloxymethyl-L-histidine

Guidance literature:: Multi-step reaction with 2 steps

1: 19 percent / Et₃N / CH₂Cl₂

2: 73 percent / aq. NaOH / methanol / 0.5 h

With sodium hydroxide; triethylamine; In methanol; dichloromethane;