4-Hydroxy-L-tryptophan

Base Information

• Chemical Name: 4-Hydroxy-L-tryptophan
• CAS No.: 25242-90-4
• Molecular Formula: C11H12N2O3
• Molecular Weight: 220.228
• Mol file: 25242-90-4.mol

Synonyms:(S)-2-Amino-3-(4-hydroxy-1H-indol-3-yl)propanoic acid;

Chemical Property of 4-Hydroxy-L-tryptophan

Chemical Property:

• PSA: 99.34000
• LogP: 1.52820
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-2-AMINO-3-(4-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Hydroxy-L-tryptophan

There total 1 articles about 4-Hydroxy-L-tryptophan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

L-Tryptophan (73-22-3,27732-43-0,80206-30-0,27813-82-7) → 7-Hydroxy-L-tryptophan (25198-02-1) + 4-Hydroxy-L-tryptophan (25242-90-4) + (S)-6-hydroxytryptophan (13567-14-1,1398507-94-2) + L-5-HTP (4350-09-8,4298-20-8)

Guidance literature:

With dihydrogen peroxide; edetate disodium; iron(II) sulfate; ascorbic acid; In water; at 22 ℃; for 0.0416667h;

Reference yield:

4-Hydroxy-L-tryptophan (25242-90-4) → [3-(2-methylaminoethyl)-1H-indol-4-yl] dihydrogen phosphate (21420-58-6,11044-29-4)

Guidance literature:

Multi-step reaction with 3 steps

1: Psilocybe cubensis enzymes PsiD / aq. buffer / 4 h / 25 °C / pH 8 / Enzymatic reaction

2: ATP / aq. buffer / 4 h / 25 °C / pH 8 / Enzymatic reaction

3: Psilocybe cubensis enzymes PsiM / aq. buffer / 4 h / 25 °C / pH 8 / Enzymatic reaction

With ATP; In aq. buffer;

DOI:10.1002/chem.201801047

upstream raw materials:

L-Tryptophan

Downstream raw materials:

[3-(2-methylaminoethyl)-1H-indol-4-yl] dihydrogen phosphate

Refernces