Z-HIS-TYR-OH

Base Information

• Chemical Name: Z-HIS-TYR-OH
• CAS No.: 17257-63-5
• Molecular Formula: C₂₃H₂₄N₄O₆
• Molecular Weight: 452.467
• Mol file: 17257-63-5.mol

Synonyms:Tyrosine,N-(N-carboxy-L-histidyl)-, N-benzyl ester, L- (6CI,7CI,8CI);Benzyloxycarbonyl-L-histidyl-L-tyrosine; NSC 333463

Chemical Property of Z-HIS-TYR-OH

Chemical Property:

• Vapor Pressure: 1.09E-32mmHg at 25°C
• Boiling Point: 874.3°C at 760 mmHg
• Flash Point: 482.6°C
• PSA: 153.64000
• Density: 1.386g/cm³
• LogP: 2.54670

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Z-HIS-TYR-OH

There total 4 articles about Z-HIS-TYR-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(Nα-benzyloxycarbonyl-histidyl)-tyrosine ethyl ester (13054-10-9) → N-(Nα-benzyloxycarbonyl-histidyl)-tyrosine (17257-63-5)

Guidance literature:

With methanol; sodium hydroxide;

Reference yield:

L-tyrosine ethyl ester (949-67-7) → N-(Nα-benzyloxycarbonyl-histidyl)-tyrosine (17257-63-5)

Guidance literature:

Multi-step reaction with 2 steps

2: methanol; NaOH

With methanol; sodium hydroxide;

Reference yield:

N-benzyloxycarbonyl-L-histidyl azide (41445-69-6) → N-(Nα-benzyloxycarbonyl-histidyl)-tyrosine (17257-63-5)

Guidance literature:

Multi-step reaction with 2 steps

2: methanol; NaOH

With methanol; sodium hydroxide;

upstream raw materials:

N-(N^α-benzyloxycarbonyl-histidyl)-tyrosine ethyl ester

L-tyrosine ethyl ester

N-benzyloxycarbonyl-L-histidyl azide