Daunorubicin mixt. with native calf thymus DNA

Base Information

• Chemical Name: Daunorubicin mixt. with native calf thymus DNA
• CAS No.: 66322-65-4
• Deprecated CAS: 95889-30-8
• Molecular Formula: C27H29NO10
• Molecular Weight: 527.5199
• European Community (EC) Number: 685-486-8
• NSC Number: 359653,304685,304684,273442,272706,272705,262649,262648,262647,262200,262199,262198,257454,257453,169533,112758
• DSSTox Substance ID: DTXSID70860259
• Wikidata: Q27166065
• ChEMBL ID: CHEMBL3560489
• Mol file: 66322-65-4.mol

Synonyms:daunorubicin semiquinone radicals

Chemical Property of Daunorubicin mixt. with native calf thymus DNA

Chemical Property:

• Vapor Pressure: 6.13E-25mmHg at 25°C
• Boiling Point: 770°Cat760mmHg
• PKA: 7.39±0.60(Predicted)
• Flash Point: 419.5°C
• PSA: 185.84000
• Density: 1.55g/cm³
• LogP: 1.72920
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 4
• Exact Mass: 527.17914612
• Heavy Atom Count: 38
• Complexity: 960

Purity/Quality:

99%min ^*data from raw suppliers

3''-epi-Daunorubicin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)C)O)N)O
• Uses: 3''-epi-Daunorubicin is an analog of Daunorubicin (D194500) which is an anthracycline antibiotic related to the rhodomycins used in the treatment of cancer.

Technology Process of Daunorubicin mixt. with native calf thymus DNA

There total 2 articles about Daunorubicin mixt. with native calf thymus DNA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 8-Acetyl-10-((2S,5S,6R)-4-amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione (20830-81-3,23942-76-9,56390-13-7,57918-20-4,57918-24-8,59092-01-2,66322-65-4,73610-99-8,75444-29-0,75444-30-3,76793-46-9,76793-47-0,76793-58-3,76793-60-7)

Guidance literature:

Verb. 6, OH^-;

DOI:10.7164/antibiotics.32.223

Reference yield:

→ 8-Acetyl-10-((2R,4R,5S,6R)-4-amino-5-hydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione (20830-81-3,23942-76-9,56390-13-7,57918-20-4,57918-24-8,59092-01-2,66322-65-4,73610-99-8,75444-29-0,75444-30-3,76793-46-9,76793-47-0,76793-58-3,76793-60-7)

Guidance literature:

Verb. 7, OH^-;

DOI:10.7164/antibiotics.32.223

Refernces