2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER

Base Information

• Chemical Name: 2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER
• CAS No.: 2570-90-3
• Molecular Formula: C9H16O3
• Molecular Weight: 172.224
• Mol file: 2570-90-3.mol

Synonyms:6-oxo-2-methyl-heptanoic acid methyl ester;Methyl 2-methyl-6-oxo-heptanoate;2-Methyl-6-oxo-heptansaeure-methylester;Heptanoic acid,2-methyl-6-oxo-,methyl ester;2-methyl-6-oxoheptanoic acid methyl ester;

Chemical Property of 2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER

Chemical Property:

• Boiling Point: 106-107 °C(Press: 11 Torr)
• PSA: 43.37000
• Density: 0.9663 g/cm3
• LogP: 1.55480

Purity/Quality:

99% ^*data from raw suppliers

2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER

There total 4 articles about 2-METHYL-6-OXO-HEPTANOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2,6-dimethyl-1-cyclohexen-1-yl acetate (6203-89-0) → dimethyl 2-methylglutarate (14035-94-0) + methyl 2-methyl-5-oxopentanoate (79664-96-3) + 6-oxo-2-methyl-heptanoic acid methyl ester (2570-90-3)

Guidance literature:

With lithium perchlorate; In methanol; acetic acid; at 2 - 3 ℃; Yield given; electrolysis;

DOI:10.1021/jo00340a009

Reference yield: 18.0%

2,6-dimethyl-1-cyclohexen-1-yl acetate (6203-89-0) → methyl 2-methyl-5-oxopentanoate (79664-96-3) + 6-oxo-2-methyl-heptanoic acid methyl ester (2570-90-3) + 2,6-dimethyl-2-cyclohexen-1-one (40790-56-5) + 2,6-dimethyl-2-methoxycyclohexanone (79664-90-7)

Guidance literature:

With lithium perchlorate; In methanol; acetic acid; Further byproducts given; electrolysis;

DOI:10.1021/jo00340a009

Reference yield:

2,6-dimethyl-1-cyclohexen-1-yl acetate (6203-89-0) → dimethyl 2-methylglutarate (14035-94-0) + methyl 2-methyl-5-oxopentanoate (79664-96-3) + 6-oxo-2-methyl-heptanoic acid methyl ester (2570-90-3) + 2,6-dimethyl-2-cyclohexen-1-one (40790-56-5) + 2,6-dimethyl-2-methoxycyclohexanone (79664-90-7)

Guidance literature:

With lithium perchlorate; In methanol; acetic acid; Product distribution; Mechanism; var. electrolysis conditions, other cycloalkanone enol acetates, var. 2-oxocycloalkan-1-ols;

DOI:10.1021/jo00340a009

upstream raw materials:

Acetic acid 2-[(6E,8E)-13-furan-3-yl-2,6,10-trimethyl-trideca-6,8-dien-(Z)-ylidene]-4-methyl-5-oxo-2,5-dihydro-furan-3-yl ester

2,6-dimethyl-1-cyclohexen-1-yl acetate

Downstream raw materials:

(+/-)-5-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)-2-methyl-pentanoic acid

(+/-)-5-(6-hydroxy-2,5,7,8-tetramethyl-chroman-2-yl)-2-methyl-pentanoic acid methyl ester

Toluene-4-sulfonic acid (2R,5R)-5-methyl-5-{4-[2-(3-methyl-but-2-enyl)-[1,3]dioxolan-2-yl]-pentyl}-[1,4]dioxan-2-ylmethyl ester

(E)-3,7-dimethyl-oct-2-ene-1,8-diol