1-Ethoxy-4-methyl-2-pentanone

Base Information

• Chemical Name: 1-Ethoxy-4-methyl-2-pentanone
• CAS No.: 14869-38-6
• Molecular Formula: C8H16 O2
• Molecular Weight: 144.2114
• Hs Code.: 2914509090
• Mol file: 14869-38-6.mol

Synonyms:NSC 244924

Chemical Property of 1-Ethoxy-4-methyl-2-pentanone

Chemical Property:

• Vapor Pressure: 0.304mmHg at 25°C
• Boiling Point: 201.7°Cat760mmHg
• Flash Point: 67.9°C
• PSA: 26.30000
• Density: 0.876g/cm³
• LogP: 1.63810

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Ethoxy-4-methyl-2-pentanone

There total 4 articles about 1-Ethoxy-4-methyl-2-pentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-diethoxy-4-methyl-pent-2-yne (51149-66-7) → 1-ethoxy-4-methyl-pentan-2-one (14869-38-6)

Guidance literature:

Multistep reaction; (i) disiamylborane, THF, (ii) aq. NaOH, aq. H₂O₂;

DOI:10.1021/ja00808a084

Reference yield:

N,N-diethyl-3-methylbutanamide (533-32-4) + ethoxymethylmagnesium chloride (4279-03-2) → 1-ethoxy-4-methyl-pentan-2-one (14869-38-6)

Guidance literature:

In tetrahydrofuran;

Reference yield:

2-ethoxyacetonitrile (62957-60-2) + isobutylmagnesium bromide (926-62-5) → 1-ethoxy-4-methyl-pentan-2-one (14869-38-6)

Guidance literature:

Zersetzen des Reaktionsprodukts mit verduennter Schwefelsaeure;

upstream raw materials:

2-ethoxyacetonitrile

isobutylmagnesium bromide

N,N-diethyl-3-methylbutanamide

ethoxymethylmagnesium chloride