(E)-benzyl prop-1-en-1-ylcarbamate

Base Information

• Chemical Name: (E)-benzyl prop-1-en-1-ylcarbamate
• CAS No.: 260967-14-4
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Mol file: 260967-14-4.mol

Synonyms:(E)-benzyl prop-1-enyl carbamate;benzyl (E)-N-prop-1-enylcarbamate;Benzyl N-[(E)-prop-1-enyl]carbamate;benzyl (E)-prop-1-enylcarbamate;O-benzyl N-(E)-prop-1-en-1-ylcarbamate;N-(E)-prop-1-enyl benzyl carbamate;Carbamic acid,(1E)-1-propenyl-,phenylmethyl ester;(E)-benzyl prop-1-en-1-ylcarbamate;

Chemical Property of (E)-benzyl prop-1-en-1-ylcarbamate

Chemical Property:

• Boiling Point: 291.7±23.0 °C(Predicted)
• PKA: 11.65±0.46(Predicted)
• PSA: 41.82000
• Density: 1.076±0.06 g/cm3(Predicted)
• LogP: 2.65080

Purity/Quality:

98% ^*data from raw suppliers

Benzyl(E)-prop-1-en-1-ylcarbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-benzyl prop-1-en-1-ylcarbamate

There total 7 articles about (E)-benzyl prop-1-en-1-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(Benzyloxycarbonyl)allylamine (5041-33-8) → O-benzyl N-(Z)-prop-1-en-1-ylcarbamate (260967-06-4) + benzyl N-[(1E)-prop-1-en-1-yl]-carbamate (260967-14-4)

Guidance literature:

With 1-C₁₀H₇Ni(P(C₆H₅)3)2Br; In methanol; at 50 ℃; for 120h; Overall yield = 48 %; Overall yield = 459 mg;

DOI:10.1002/adsc.201500461

Reference yield:

N-benzyloxycarbonyl-L-treonine (19728-63-3) → benzyl N-[(1E)-prop-1-en-1-yl]-carbamate (260967-14-4)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at -78 - 20 ℃;

Reference yield:

trans-Crotonyl-azid + benzyl alcohol (100-51-6,185532-71-2) → benzyl N-[(1E)-prop-1-en-1-yl]-carbamate (260967-14-4)

Guidance literature:

With pyridine; hydroquinone; In toluene; at 120 ℃; for 0.5h;

DOI:10.1055/s-0034-1380723

upstream raw materials:

benzyl alcohol

O-benzyl carbamate

N-benzyloxycarbonyl-L-treonine

N-(Benzyloxycarbonyl)allylamine

Downstream raw materials:

benzyl ((1R,2S)-2-bromo-1-(2,5-dioxopyrrolidin-1-yl)propyl)carbamate

benzyl ((1S,2R)-2-bromo-1-(2,5-dioxopyrrolidin-1-yl)propyl)carbamate

methyl 4-(((1S,2S)-1-(((benzyloxy)carbonyl)amino)-2-bromopropyl)amino)-4-oxobutanoate