Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

Base Information

Chemical Name:Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate
CAS No.:261620-76-2
Molecular Formula:C14H21NO3
Molecular Weight:251.32100
Hs Code.:
DSSTox Substance ID:DTXSID30701735
Mol file:261620-76-2.mol

Synonyms:DTXSID30701735;TERT-BUTYL 10-OXO-9-AZABICYCLO[6.2.0]DEC-4-ENE-9-CARBOXYLATE;261620-76-2

Suppliers and Price of Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

Chemical Property:

PSA：46.61000
LogP:2.81660
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:251.15214353
Heavy Atom Count:18
Complexity:381

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C2CCC=CCCC2C1=O

Technology Process of Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

There total 3 articles about Tert-butyl 10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 24424-99-5
di-tert-butyl dicarbonate

: (±)-(Z)-9-azabicyclo[6.2.0]dec-4-en-10-one

: 261620-76-2
(±)-tert-butyl (Z)-10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

Guidance literature:: With dmap; In acetonitrile; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201801209

Reference yield: 70.0%

: 4946-37-6
3-azabicyclo<6.2.0>dec-7-ene-2-one

: 24424-99-5
di-tert-butyl dicarbonate

: 261620-76-2
3-(tert-butoxycarbonyl)-3-azabicyclo[6.2.0]dec-7-ene-2-one

Guidance literature:: With dmap; In acetonitrile; at 20 ℃; for 12h;
DOI:10.1016/S0040-4020(99)00909-6

Reference yield:

: 1552-12-1,111-78-4
1,5-cis,cis-cyclooctadiene

: 261620-76-2
(±)-tert-butyl (Z)-10-oxo-9-azabicyclo[6.2.0]dec-4-ene-9-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / dichloromethane / 0 - 20 °C / Inert atmosphere

2: dmap / acetonitrile / 0 - 20 °C / Inert atmosphere

With dmap; sodium carbonate; In dichloromethane; acetonitrile;
DOI:10.1002/ejoc.201801209