Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester

Base Information

Chemical Name:Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester
CAS No.:263165-29-3
Molecular Formula:C13H19O5P
Molecular Weight:286.265
Hs Code.:
DSSTox Substance ID:DTXSID50443842
Wikidata:Q82261811

Synonyms:Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester;263165-29-3;SCHEMBL12229698;DTXSID50443842

Suppliers and Price of Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:286.09701070
Heavy Atom Count:19
Complexity:306

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C1=CC=CC(=C1)C2OCCO2)OCC

Technology Process of Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester

There total 1 articles about Phosphonic acid, [3-(1,3-dioxolan-2-yl)phenyl]-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 17789-14-9
3-(1,3-dioxolan-2-yl)-phenylbromide

Diethyl phosphonate: 762-04-9,123-22-8
Diethyl phosphonate

: 263165-29-3
Diethyl 3-(dioxolan-2'-yl)phenylphosphonate

Guidance literature:: With triethylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 95 ℃; for 12h;
DOI:10.1039/a906507e

Reference yield: 90.0%

: 263165-29-3
Diethyl 3-(dioxolan-2'-yl)phenylphosphonate

: 63818-48-4
(3-formylphenyl)phosphonic acid diethyl ester

Guidance literature:: With sulfuric acid; silica gel; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1039/a906507e

Reference yield:

: 263165-29-3
Diethyl 3-(dioxolan-2'-yl)phenylphosphonate

: 263165-30-6
Diethyl [3-(diethoxyphosphoryl)phenyl]hydroxymethylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / H₂SO₄; silica gel / CH₂Cl₂ / 24 h / 20 °C

2: 53 percent / NEt₃N / 36 h / 20 °C

With sulfuric acid; silica gel; triethylamine; In dichloromethane; 1: Ring cleavage / 2: Substitution;
DOI:10.1039/a906507e