2-(4-morpholin-4-ylphenyl)acetic Acid

Base Information

Chemical Name:2-(4-morpholin-4-ylphenyl)acetic Acid
CAS No.:26577-57-1
Molecular Formula:C12H15NO3
Molecular Weight:221.256
Hs Code.:
European Community (EC) Number:841-130-5
DSSTox Substance ID:DTXSID90400358
Nikkaji Number:J3.206.551A
Wikidata:Q82203295
Mol file:26577-57-1.mol

Synonyms:26577-57-1;2-(4-morpholin-4-ylphenyl)acetic Acid;2-(4-Morpholinophenyl)acetic acid;4-Morpholinophenylacetic Acid;(4-Morpholin-4-ylphenyl)acetic acid;MFCD01995085;2-[4-(morpholin-4-yl)phenyl]acetic acid;Oprea1_314036;4-Morpholinobenzeneacetic acid;SCHEMBL2649726;2-(4-Morpholinophenyl)aceticacid;DTXSID90400358;JCUCSMGLJLRTMT-UHFFFAOYSA-N;BBA57757;AC5766;AKOS015948257;(4-morpholin-4-yl-phenyl)-acetic acid;SY248643;TS-03162;CS-0450528;FT-0761697;EN300-196941

Suppliers and Price of 2-(4-morpholin-4-ylphenyl)acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-Morpholin-4-ylphenyl)aceticAcid
50mg
$ 90.00

Matrix Scientific
(4-Morpholin-4-ylphenyl)acetic acid 97%
1g
$ 524.00

Crysdot
2-(4-Morpholinophenyl)aceticacid 97%
1g
$ 325.00

Atlantic Research Chemicals
(4-Morpholin-4-ylphenyl)aceticacid 95%
1gm:
$ 212.07

American Custom Chemicals Corporation
(4-MORPHOLIN-4-YLPHENYL)ACETIC ACID 95.00%
5MG
$ 496.30

AK Scientific
2-(4-Morpholin-4-ylphenyl)aceticAcid
5g
$ 998.00

Total 6 raw suppliers

Chemical Property of 2-(4-morpholin-4-ylphenyl)acetic Acid

Chemical Property:

PSA：49.77000
LogP:1.21530
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:221.10519334
Heavy Atom Count:16
Complexity:230

Purity/Quality:

99%, ^*data from raw suppliers

(4-Morpholin-4-ylphenyl)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CC=C(C=C2)CC(=O)O

Technology Process of 2-(4-morpholin-4-ylphenyl)acetic Acid

There total 3 articles about 2-(4-morpholin-4-ylphenyl)acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 39911-99-4
ethyl 4-(morpholin-4-yl)phenylacetate

: 26577-57-1
4-(morpholin-4-yl)phenylacetic acid

Guidance literature:: ethyl 4-(morpholin-4-yl)phenylacetate; With methanol; lithium hydroxide; water; at 20 ℃; for 3h;

With hydrogenchloride; water;

Reference yield:

: 110-91-8,99108-56-2
morpholine

: 39910-98-0
4-morpholinoacetophenone

concentrated acetic acid: concentrated acetic acid

: 26577-57-1
4-(morpholin-4-yl)phenylacetic acid

Guidance literature:: With sulfuric acid; hydrogen sulfide; In water;

Reference yield:

: 14062-25-0
Ethyl 4-bromophenylacetate

: 26577-57-1
4-(morpholin-4-yl)phenylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; XPhos; caesium carbonate / toluene / 12 h / 100 °C / Inert atmosphere

2: potassium hydroxide / methanol; water / 8 h / 20 °C

With palladium diacetate; caesium carbonate; potassium hydroxide; XPhos; In methanol; water; toluene;
DOI:10.1039/c3cc44438d