4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol

Base Information

Chemical Name:4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol
CAS No.:26902-85-2
Molecular Formula:C10H11F3O2
Molecular Weight:220.191
Hs Code.:
DSSTox Substance ID:DTXSID701259908

Synonyms:26902-85-2;4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol;1-(4-ethoxyphenyl)-2,2,2-trifluoroethan-1-ol;Benzenemethanol, 4-ethoxy-alpha-(trifluoromethyl)-;DXDZDJCNLJXFQC-UHFFFAOYSA-N;DTXSID701259908;MFCD12786973;SY250319;4-Ethoxy-alpha-(trifluoromethyl)benzenemethanol;EN300-1933246

Suppliers and Price of 4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:220.07111408
Heavy Atom Count:15
Complexity:186

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=CC=C(C=C1)C(C(F)(F)F)O

Technology Process of 4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol

There total 4 articles about 4-Ethoxy-alpha-(trifluoromethyl)benzyl Alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 407-38-5
2,2,2-trifluoroethyl trifluoroacetate

: 699-08-1
1-ethoxy-4-iodobenzene

: 26902-85-2
2,2,2-trifluoro-1-(4-ethoxyphenyl)ethan-1-ol

Guidance literature:: 1-ethoxy-4-iodobenzene; With TurboGrignard; toluene; In tetrahydrofuran; at -15 ℃; for 0.416667h; Inert atmosphere;

2,2,2-trifluoroethyl trifluoroacetate; In tetrahydrofuran; toluene; at 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1002/ejoc.202000550

Reference yield: 78.0%

: 431-47-0
trifluoroacetic acid-methyl ester

: 699-08-1
1-ethoxy-4-iodobenzene

: 26902-85-2
2,2,2-trifluoro-1-(4-ethoxyphenyl)ethan-1-ol

Guidance literature:: 1-ethoxy-4-iodobenzene; With TurboGrignard; toluene; In tetrahydrofuran; at -40 - 0 ℃; for 0.416667h; Inert atmosphere;

trifluoroacetic acid-methyl ester; In tetrahydrofuran; toluene; at -40 ℃; Inert atmosphere;
DOI:10.1002/ejoc.202000550