6-Aminoquinoline

Base Information Edit

Chemical Name:6-Aminoquinoline
CAS No.:580-15-4
Molecular Formula:C9H8N2
Molecular Weight:144.176
Hs Code.:29334900
European Community (EC) Number:209-453-0
NSC Number:58388
UNII:XN7T264NL4
DSSTox Substance ID:DTXSID80206725
Nikkaji Number:J79.670K
Wikidata:Q27460051
ChEMBL ID:CHEMBL99408
Mol file:580-15-4.mol

Synonyms:6-aminoquinoline

Suppliers and Price of 6-Aminoquinoline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Aminoquinoline
10g
$ 150.00

TRC
6-Aminoquinoline
1g
$ 45.00

TCI Chemical
6-Aminoquinoline >99.0%(T)
1g
$ 20.00

TCI Chemical
6-Aminoquinoline >99.0%(T)
5g
$ 75.00

SynQuest Laboratories
6-Aminoquinoline 98%
5 g
$ 37.00

SynQuest Laboratories
6-Aminoquinoline 98%
1 g
$ 16.00

Sigma-Aldrich
6-Aminoquinoline 98%
1g
$ 45.80

Sigma-Aldrich
6-Aminoquinoline 98%
5g
$ 129.00

Oakwood
6-Aminoquinoline 97%
1g
$ 10.00

Medical Isotopes, Inc.
6-Aminoquinoline 98%
5 g
$ 343.00

Total 116 raw suppliers

Chemical Property of 6-Aminoquinoline Edit

Chemical Property:

Appearance/Colour:dark yellow to brown crystalline powder
Vapor Pressure:4.66E-06mmHg at 25°C
Melting Point:115-119 °C(lit.)
Refractive Index:1.7080 (estimate)
Boiling Point:377.2 °C at 760 mmHg
PKA:pK1: 5.63(+1) (20°C,μ=0.01)
Flash Point:181.9 °C
PSA：38.91000
Density:1.1148 (estimate)
LogP:2.39820
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Sensitive.:Air Sensitive
Solubility.:Chloroform, DMSO, Methanol
Water Solubility.:Soluble in methanol, chloroform, ethanol, and benzene. Insoluble in water.
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:144.068748264
Heavy Atom Count:11
Complexity:136

Purity/Quality:

99% ^*data from raw suppliers

6-Aminoquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi，Xn
Hazard Codes:Xi,Xn
Statements: 36/38-36/37/38-20/21/22
Safety Statements: 26-36-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2)N)N=C1
Uses 6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. 6-Aminoquinoline was used as an internal standard in determining serum nicotine and cotinine simultaneously by using high-performance liquid chromatography (HPLC)-fluorometric detection with a postcolumn ultraviolet-photoirradiation system. It was also used as a fluorescent derivatizing agent for the detection of biochemicals and in the synthesis of tertiary N-methylated enaminonesa.

Technology Process of 6-Aminoquinoline

There total 80 articles about 6-Aminoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 613-50-3
6-nitroquinoline

: 580-15-4
6-aminoquinoline

Guidance literature:: With potassium fluoride; polymethylhydrosiloxane; palladium diacetate; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1055/s-2006-950231

Reference yield: 99.0%

: 612-57-7
6-chloroquinoline

: 580-15-4
6-aminoquinoline

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; ammonia; sodium t-butanolate; In 1,4-dioxane; at 65 ℃; chemoselective reaction; Inert atmosphere;
DOI:10.1002/anie.201000526

Reference yield: 98.0%

: 5332-25-2
6-bromoquinoline

: 580-15-4
6-aminoquinoline

Guidance literature:: With copper(I) oxide; ammonium hydroxide; N¹-(furan-2-ylmethyl)-N²-(2-methylnaphthalen-1-yl)oxalamide; potassium hydroxide; In ethanol; at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.7b00901