Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate

Base Information

Chemical Name:Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate
CAS No.:27475-15-6
Molecular Formula:C10H9BrO4
Molecular Weight:273.083
Hs Code.:
DSSTox Substance ID:DTXSID901265660

Synonyms:Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate;27475-15-6;DTXSID901265660

Suppliers and Price of Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:271.96842
Heavy Atom Count:15
Complexity:254

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C=C(C=C1)C(=O)CBr)O

Technology Process of Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate

There total 4 articles about Methyl 4-(2-bromoacetyl)-2-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 27475-10-1
4-Acetyl-2-benzyloxy-benzoic acid methyl ester

: 27475-15-6
4-(2-Bromo-acetyl)-2-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C

2: Br₂

With hydrogen; bromine; palladium on activated charcoal;
DOI:10.1021/jm00298a022

Reference yield:

: 27727-70-4
methyl 4-amino-2-(benzyloxy)benzoate

: 27475-15-6
4-(2-Bromo-acetyl)-2-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NaNO₂, aq. HCl, (ii) /BRN= 1209252/, CuSO₄, Na₂SO₃, NaOAc

2: H₂ / Pd-C

3: Br₂

With hydrogen; bromine; palladium on activated charcoal;
DOI:10.1021/jm00298a022

Reference yield:

: 4136-97-4
methyl 4-aminosalicylate

: 27475-15-6
4-(2-Bromo-acetyl)-2-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: aq. NaOH

2: (i) NaNO₂, aq. HCl, (ii) /BRN= 1209252/, CuSO₄, Na₂SO₃, NaOAc

3: H₂ / Pd-C

4: Br₂

With sodium hydroxide; hydrogen; bromine; palladium on activated charcoal;
DOI:10.1021/jm00298a022