3'-O-acetyl-5'-amino-5'-deoxythymidine

Base Information

Chemical Name:3'-O-acetyl-5'-amino-5'-deoxythymidine
CAS No.:27930-49-0
Molecular Formula:C12H17N3O5
Molecular Weight:283.28000
Hs Code.:
DSSTox Substance ID:DTXSID60563904
Nikkaji Number:J109.860H
Wikidata:Q82448415
Mol file:27930-49-0.mol

Synonyms:3'-O-acetyl-5'-amino-5'-deoxythymidine;27930-49-0;SCHEMBL8659542;DTXSID60563904;KIDWNDSBSZGYKG-IVZWLZJFSA-N

Suppliers and Price of 3'-O-acetyl-5'-amino-5'-deoxythymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3'-O-acetyl-5'-amino-5'-deoxythymidine

Chemical Property:

PKA:9.55±0.10(Predicted)
PSA：116.67000
Density:1.37±0.1 g/cm3(Predicted)
LogP:0.13550
XLogP3:-1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:283.11682065
Heavy Atom Count:20
Complexity:476

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CN(C(=O)NC1=O)C2CC(C(O2)CN)OC(=O)C
Isomeric SMILES:CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CN)OC(=O)C

Technology Process of 3'-O-acetyl-5'-amino-5'-deoxythymidine

There total 3 articles about 3'-O-acetyl-5'-amino-5'-deoxythymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.1%

: 27766-92-3
3'-O-acetyl-5'-azido-5'-deoxythymidine

: 27930-49-0
3'-O-acetyl-5'-amino-5'-deoxythymidine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 12h; Ambient temperature;
DOI:10.1080/07328319608002452

Reference yield:

: 19316-85-9
5'-azido-5'-deoxythymidine

: 27930-49-0
3'-O-acetyl-5'-amino-5'-deoxythymidine

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / pyridine / 15 h

2: 85.1 percent / hydrogen / 10percent palladium on carbon / ethanol / 12 h / Ambient temperature

With pyridine; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1080/07328319608002452