2-amino-2-deoxy-beta-arabinofuranosylguanine

Base Information

Chemical Name:2-amino-2-deoxy-beta-arabinofuranosylguanine
CAS No.:69427-81-2
Molecular Formula:C₁₀H₁₄N₆O₄
Molecular Weight:282.259
Hs Code.:
Mol file:69427-81-2.mol

Synonyms:2-amino-2-deoxy-beta-arabinofuranosylguanine

Suppliers and Price of 2-amino-2-deoxy-beta-arabinofuranosylguanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-amino-2-deoxy-beta-arabinofuranosylguanine

Chemical Property:

Vapor Pressure:7.53E-24mmHg at 25°C
Boiling Point:753.4°C at 760 mmHg
Flash Point:409.4°C
PSA：165.56000
Density:2.25g/cm³
LogP:-1.02650

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-amino-2-deoxy-beta-arabinofuranosylguanine

There total 8 articles about 2-amino-2-deoxy-beta-arabinofuranosylguanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 193885-49-3,215943-79-6
2,6-diamino-9-(2-amino-2-deoxy-β-D-arabinofuranosyl)purine

: 69427-81-2
2-amino-9-(2-amino-β-D-2-deoxy-arabinofuranosyl)-1,9-dihydro-purin-6-one

Guidance literature:: With adenosine aminohydrolase (EC 3.5.4.4); In dimethyl sulfoxide; for 360h; Ambient temperature; pH 6.5;
DOI:10.1139/v97-092

Reference yield:

: 87791-88-6
3′,5′-(1,1,3,3-tetraisopropyl-1,3-disiloxan-1,3-yl)-9-(β-D-ribofuranosyl)purin-2,6-diamine

: 69427-81-2
2-amino-9-(2-amino-β-D-2-deoxy-arabinofuranosyl)-1,9-dihydro-purin-6-one

Guidance literature:: Multi-step reaction with 5 steps

1: DMAP / CH₂Cl₂ / 0.5 h / 0 °C

2: LiN₃ / dimethylformamide / Ambient temperature

3: tetrabutylammonium fluoride / tetrahydrofuran / Ambient temperature

4: 85 percent / hydrazine / Raney Ni / ethanol; H₂O / 6 h / Ambient temperature

5: 90 percent / adenosine aminohydrolase (EC 3.5.4.4) / dimethylsulfoxide / 360 h / Ambient temperature; pH 6.5

With dmap; lithium azide; adenosine aminohydrolase (EC 3.5.4.4); tetrabutyl ammonium fluoride; hydrazine; nickel; In tetrahydrofuran; ethanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1139/v97-092

Reference yield:

: 193885-46-0
2,6-diamino-9-(2-azido-2-deoxy-β-D-arabinofuranosyl)purine

: 69427-81-2
2-amino-9-(2-amino-β-D-2-deoxy-arabinofuranosyl)-1,9-dihydro-purin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / hydrazine / Raney Ni / ethanol; H₂O / 6 h / Ambient temperature

2: 90 percent / adenosine aminohydrolase (EC 3.5.4.4) / dimethylsulfoxide / 360 h / Ambient temperature; pH 6.5

With adenosine aminohydrolase (EC 3.5.4.4); hydrazine; nickel; In ethanol; water; dimethyl sulfoxide;
DOI:10.1139/v97-092