4,6-Dichloroisophthaloyl dichloride

Base Information

• Chemical Name: 4,6-Dichloroisophthaloyl dichloride
• CAS No.: 2855-01-8
• Molecular Formula: C8H2Cl4O2
• Molecular Weight: 271.91200
• Mol file: 2855-01-8.mol

Synonyms:4,6-dichloro-isophthaloyl chloride;4,6-Dichlor-isophthaloylchlorid;4,6-Dichlor-isophthalsaeure-dichlorid;4.6-Dichlor-isophthalsaeuredichlorid;4,6-Dichlorisophthalsaeure-dichlorid;

Chemical Property of 4,6-Dichloroisophthaloyl dichloride

Chemical Property:

• PSA: 34.14000
• LogP: 3.75140

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,6-Dichloroisophthaloyl dichloride

There total 6 articles about 4,6-Dichloroisophthaloyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

4,6-dichlorobenzene-1,3-dicarboxylic acid (6660-65-7) → 4,6-dichlorobenzene-1,3-dicarboxylic acid dichloride (2855-01-8)

Guidance literature:

With phosphorus pentachloride; In tetrachloromethane; for 4h; Heating;

DOI:10.1039/a606932k

Reference yield:

→ 4,6-dichlorobenzene-1,3-dicarboxylic acid dichloride (2855-01-8)

Guidance literature:

With thionyl chloride; at 240 ℃; im Rohr;

Reference yield:

4,6-dichloro-1,3-dimethylbenzene (2084-45-9) → 4,6-dichlorobenzene-1,3-dicarboxylic acid dichloride (2855-01-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / conc. HNO₃ (d=1.4) / nitrobenzene / 30 h / 150 - 180 °C

2: 86 percent / PCl₅ / CCl₄ / 4 h / Heating

With phosphorus pentachloride; nitric acid; In tetrachloromethane; nitrobenzene;

DOI:10.1039/a606932k

upstream raw materials:

4,6-dichlorobenzene-1,3-dicarboxylic acid

thionyl chloride

4,6-dimethyl-benzene-1,3-disulfonyl chloride

4,6-dichloro-1,3-dimethylbenzene

Downstream raw materials:

4,6-bismethylthio-1,3-diacetylbenzene

4,6-dichloro-1,3-diacetylbenzene

4,6-dichlorobenzene-1,3-dicarboxylic acid

4,6-dichloro-isophthalic acid dimethyl ester

Refernces

• 1、 McKinnon, David M.,Abouzeid, Azza A.. "The Synthesis of some Benzodiisothiazoles". . p. 445 - 448. Retrieved 2007/10/02.