2-(5-Acetyl-6-hydroxycoumaran-2-yl)-2-propenyl=acetate

Base Information

• Chemical Name: 2-(5-Acetyl-6-hydroxycoumaran-2-yl)-2-propenyl=acetate
• CAS No.: 29147-46-4
• Molecular Formula: C15H16O5
• Molecular Weight: 276.28500
• Mol file: 29147-46-4.mol

Synonyms:Acetic acid 2-(5-acetyl-6-hydroxy-2,3-dihydro-benzofuran-2-yl)-allyl ester;

Chemical Property of 2-(5-Acetyl-6-hydroxycoumaran-2-yl)-2-propenyl=acetate

Chemical Property:

• PSA: 72.83000
• LogP: 2.01760

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(5-Acetyl-6-hydroxycoumaran-2-yl)-2-propenyl=acetate

There total 3 articles about 2-(5-Acetyl-6-hydroxycoumaran-2-yl)-2-propenyl=acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.5%

2-<1-(acetoxymethyl)vinyl>-5-acetyl-6-methoxy-2,3-dihydrobenzofuran (86948-55-2) → (+/-)-dihydroageratone (29147-46-4)

Guidance literature:

With magnesium iodide; In benzene; for 3h;

DOI:10.1246/bcsj.57.3607

Reference yield:

2-isopropenyl-6-methoxy-2,3-dihydrobenzofuran (91301-18-7) → (+/-)-dihydroageratone (29147-46-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 7.1 percent / SeO₂ / 7 h / Heating

2: 48.3 percent / (CF₃CO)2O / 3 h / Ambient temperature

3: 20.5 percent / MgI₂*Et₂O / benzene / 3 h

With selenium(IV) oxide; trifluoroacetic anhydride; magnesium iodide; In benzene;

DOI:10.1246/bcsj.57.3607

Reference yield:

2-<1-(acetoxymethyl)vinyl>-6-methoxy-2,3-dihydrobenzofuran (95245-05-9) → (+/-)-dihydroageratone (29147-46-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 48.3 percent / (CF₃CO)2O / 3 h / Ambient temperature

2: 20.5 percent / MgI₂*Et₂O / benzene / 3 h

With trifluoroacetic anhydride; magnesium iodide; In benzene;

DOI:10.1246/bcsj.57.3607

upstream raw materials:

2-<1-(acetoxymethyl)vinyl>-5-acetyl-6-methoxy-2,3-dihydrobenzofuran

2-isopropenyl-6-methoxy-2,3-dihydrobenzofuran

2-<1-(acetoxymethyl)vinyl>-6-methoxy-2,3-dihydrobenzofuran