(3R)-3-methyl-5-oxo-d-proline

Base Information

Chemical Name:(3R)-3-methyl-5-oxo-d-proline
CAS No.:291763-98-9
Molecular Formula:C6H9NO3
Molecular Weight:143.142
Hs Code.:
DSSTox Substance ID:DTXSID00514197
Nikkaji Number:J1.336.989E
Wikidata:Q82374378
Mol file:291763-98-9.mol

Synonyms:291763-98-9;(3R)-3-methyl-5-oxo-d-proline;(2R,3R)-3-methyl-5-oxopyrrolidine-2-carboxylic acid;trans-3-Methyl-5-oxo-pyrrolidine-2-carboxylic acid;(2R,3R)-3-Methyl-5-oxo-pyrrolidine-2-carboxylic acid;DTXSID00514197

Suppliers and Price of (3R)-3-methyl-5-oxo-d-proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3R)-3-methyl-5-oxo-d-proline

Chemical Property:

XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:143.058243149
Heavy Atom Count:10
Complexity:178

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC(=O)NC1C(=O)O
Isomeric SMILES:C[C@@H]1CC(=O)N[C@H]1C(=O)O

Technology Process of (3R)-3-methyl-5-oxo-d-proline

There total 2 articles about (3R)-3-methyl-5-oxo-d-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: C₃₄H₂₈N₄O₆^(2-)*Ni⁽²⁺⁾

: 124522-52-7
pyridine-2-carboxylic acid(2-benzoyl-phenyl)-amide

: 90319-52-1,7480-32-2
(4R)-phenyl-2-oxazolidinone

: 291763-98-9
(2R,3R)-3-methylpyroglutamic acid

Guidance literature:: C₃₄H₂₈N₄O₆^(2-)*Ni⁽²⁺⁾; With hydrogenchloride; In methanol; at 70 ℃;

With ammonium hydroxide; In water;
DOI:10.1021/jo0495438

Reference yield:

: 148766-15-8
(R,E)-3-but-2-enoyl-4-phenyloxazolidin-2-one

: 90319-52-1,7480-32-2
(4R)-phenyl-2-oxazolidinone

: 291763-98-9
(2R,3R)-3-methylpyroglutamic acid

Guidance literature:: (R,E)-3-but-2-enoyl-4-phenyloxazolidin-2-one; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 20 ℃;

With hydrogenchloride; In methanol; Title compound not separated from byproducts;
DOI:10.1055/s-2006-926252

Reference yield: 67.0%

: 291763-98-9
(2R,3R)-3-methylpyroglutamic acid

: 97550-61-3,274255-87-7
(2R,3R)-2-amino-3-methylpentanedioic acid

Guidance literature:: (2R,3R)-3-methylpyroglutamic acid; With hydrogenchloride; for 12h; Heating;

With methyloxirane; In ethanol; Heating;
DOI:10.1021/ol0623668