1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride

Base Information

Chemical Name:1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride
CAS No.:102280-85-3
Molecular Formula:C₂₀H₂₅N₅O*2ClH
Molecular Weight:424.373
Hs Code.:
DSSTox Substance ID:DTXSID00144872
Mol file:102280-85-3.mol

Synonyms:1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride;102280-85-3;1-Benzyl-6-(4-methyl-1-piperazinyl)-7-aminocarbonyl-5-azaindole dihydrochloride;DTXSID00144872

Suppliers and Price of 1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:423.1592659
Heavy Atom Count:28
Complexity:487

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=NC=C3CCN(C3=C2C(=O)N)CC4=CC=CC=C4.Cl.Cl

Technology Process of 1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride

There total 2 articles about 1H-Pyrrolo(3,2-c)pyridine-7-carboxamide, 2,3-dihydro-1-benzyl-6-(4-methyl-1-piperazinyl)-, dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 109-01-3
1-methyl-piperazine

: 74976-29-7
1-benzyl-6-chloro-7-aminocarbonyl-5-azaindoline

: 102280-85-3
1-benzyl-6-(4-methyl-1-piperazinyl)-7-aminocarbonyl-5-azaindoline dihydrochloride

Guidance literature:: at 180 - 185 ℃; for 10h;
DOI:10.1007/BF00777399

Reference yield:

: 66751-32-4
1-benzyl-6-chloro-7-cyano-5-azaindoline

: 102280-85-3
1-benzyl-6-(4-methyl-1-piperazinyl)-7-aminocarbonyl-5-azaindoline dihydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 95.5 percent / 7percent aq. NaOH / 100 h / Heating

2: 65 percent / 10 h / 180 - 185 °C

With sodium hydroxide;
DOI:10.1007/BF00777399