3-Phenylbicyclo[1.1.0]butane-1-carbonitrile

Base Information

Chemical Name:3-Phenylbicyclo[1.1.0]butane-1-carbonitrile
CAS No.:30494-27-0
Molecular Formula:C11H9N
Molecular Weight:155.199
Hs Code.:
DSSTox Substance ID:DTXSID80507047
Nikkaji Number:J801.703D
Wikidata:Q82363068
Mol file:30494-27-0.mol

Synonyms:3-Phenylbicyclo[1.1.0]butane-1-carbonitrile;30494-27-0;DTXSID80507047

Suppliers and Price of 3-Phenylbicyclo[1.1.0]butane-1-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-Phenylbicyclo[1.1.0]butane-1-carbonitrile

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:155.073499291
Heavy Atom Count:12
Complexity:258

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2(C1(C2)C3=CC=CC=C3)C#N

Technology Process of 3-Phenylbicyclo[1.1.0]butane-1-carbonitrile

There total 6 articles about 3-Phenylbicyclo[1.1.0]butane-1-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 30494-26-9
3-chloro-3-phenyl-1-cyclobutanecarbonitrile

: 30494-27-0
3-phenylbicyclo<1.1.0>butanecarbonitrile

Guidance literature:: With potassium tert-butylate; hydroquinone; In tetrahydrofuran; at 20 ℃; for 5h;

Reference yield: 43.0%

: 7321-55-3
2,2-dimethylmalononitrile

: C₁₀H₉Br₂Cl

: 30494-27-0
3-phenylbicyclo<1.1.0>butanecarbonitrile

Guidance literature:: C₁₀H₉Br₂Cl; With methyllithium; In diethyl ether; at -78 ℃; for 1.25h; Inert atmosphere;

With tert.-butyl lithium; In diethyl ether; pentane; at -78 ℃; for 1.25h; Inert atmosphere;

2,2-dimethylmalononitrile; In tetrahydrofuran; diethyl ether; pentane; at -78 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.6b02051