Technology Process of norsegoline
There total 11 articles about norsegoline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dichloro bis(acetonitrile) palladium(II); 1,10-Phenanthroline; molybdenum hexacarbonyl;
In
1,2-dichloro-ethane;
at 120 ℃;
for 3h;
Schlenk technique;
Inert atmosphere;
DOI:10.1002/cjoc.202100094
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: orthoformic acid triethyl ester / 2 h / 90 °C / Inert atmosphere
1.2: 2 h / 90 °C / Inert atmosphere
2.1: phosphorus pentachloride; trichlorophosphate / 4 h / Reflux; Inert atmosphere
3.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; toluene / 120 °C / Inert atmosphere
4.1: dichloro bis(acetonitrile) palladium(II); 1,10-Phenanthroline; molybdenum hexacarbonyl / 1,2-dichloro-ethane / 3 h / 120 °C / Schlenk technique; Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); tetrakis(triphenylphosphine) palladium(0); 1,10-Phenanthroline; phosphorus pentachloride; potassium carbonate; orthoformic acid triethyl ester; molybdenum hexacarbonyl; trichlorophosphate;
In
ethanol; 1,2-dichloro-ethane; toluene;
DOI:10.1002/cjoc.202100094
- Guidance literature:
-
Multi-step reaction with 3 steps
1: phosphorus pentachloride; trichlorophosphate / 4 h / Reflux; Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / ethanol; toluene / 120 °C / Inert atmosphere
3: dichloro bis(acetonitrile) palladium(II); 1,10-Phenanthroline; molybdenum hexacarbonyl / 1,2-dichloro-ethane / 3 h / 120 °C / Schlenk technique; Inert atmosphere
With
dichloro bis(acetonitrile) palladium(II); tetrakis(triphenylphosphine) palladium(0); 1,10-Phenanthroline; phosphorus pentachloride; potassium carbonate; molybdenum hexacarbonyl; trichlorophosphate;
In
ethanol; 1,2-dichloro-ethane; toluene;
DOI:10.1002/cjoc.202100094
