Ethyl 2-(3-hydroxypropoxy)benzoate

Base Information

Chemical Name:Ethyl 2-(3-hydroxypropoxy)benzoate
CAS No.:30721-19-8
Molecular Formula:C12H16O4
Molecular Weight:224.25300
Hs Code.:
DSSTox Substance ID:DTXSID10535414
Wikidata:Q82409715
Mol file:30721-19-8.mol

Synonyms:ETHYL 2-(3-HYDROXYPROPOXY)BENZOATE;30721-19-8;DTXSID10535414

Suppliers and Price of Ethyl 2-(3-hydroxypropoxy)benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of Ethyl 2-(3-hydroxypropoxy)benzoate

Chemical Property:

Boiling Point:198-200 °C(Press: 15 Torr)
PSA：55.76000
Density:1.130±0.06 g/cm3(Predicted)
LogP:1.62450
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:224.10485899
Heavy Atom Count:16
Complexity:205

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC=CC=C1OCCCO

Technology Process of Ethyl 2-(3-hydroxypropoxy)benzoate

There total 1 articles about Ethyl 2-(3-hydroxypropoxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 30721-19-8
ethyl 2-(3-hydroxypropoxy)benzoate

Guidance literature:: Chlorpropanol, Na-Aethylsalicylat;

Reference yield: 83.0%

: 30721-19-8
ethyl 2-(3-hydroxypropoxy)benzoate

: 93622-59-4
ethyl 2-(3-chloropropoxy)benzoate

Guidance literature:: With thionyl chloride; In pyridine; benzene; for 17h; Heating;
DOI:10.1246/bcsj.57.1976

Reference yield:

: 30721-19-8
ethyl 2-(3-hydroxypropoxy)benzoate

: 88628-77-7
1-<3-(o-carboxyphenoxy)propoxy>-2-<3-(8-quinolyloxy)propoxy>-4-t-butylbenzene

Guidance literature:: Multi-step reaction with 4 steps

1: 83 percent / thionyl chloride / pyridine; benzene / 17 h / Heating

2: 1.) t-BuOK / 1.) DMF; 2.) 70 deg C, 48 h

3: 1.) t-BuOK; 2.) KI / 1.) DMSO; 2.) 70 deg C, 4 d

4: 79 percent / KOH / ethanol / Heating; overnight

With potassium hydroxide; thionyl chloride; potassium tert-butylate; potassium iodide; In pyridine; ethanol; benzene;
DOI:10.1246/bcsj.57.1976