2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Base Information

Chemical Name:2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
CAS No.:309736-20-7
Molecular Formula:C14H13NO3S
Molecular Weight:275.32300
Hs Code.:
Mol file:309736-20-7.mol

Synonyms:2-(2-Formyl-pyrrol-1-yl)-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid;

Suppliers and Price of 2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
2-(2-FORMYL-1H-PYRROL-1-YL)-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLIC ACID 95.00%
5MG
$ 502.41

Total 1 raw suppliers

Chemical Property of 2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Chemical Property:

PSA：87.54000
LogP:2.92830

Purity/Quality:

99% ^*data from raw suppliers

2-(2-FORMYL-1H-PYRROL-1-YL)-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

There total 3 articles about 2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 847021-84-5
methyl 2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

: 309736-20-7
2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; water; for 3h; Heating;
DOI:10.1021/jo048204b

Reference yield:

: 728882-85-7
methyl 2-(1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate

: 309736-20-7
2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / POCl₃ / 5 h / 50 - 60 °C

2: 67 percent / KOH / H₂O; methanol / 3 h / Heating

With potassium hydroxide; trichlorophosphate; In methanol; water;
DOI:10.1021/jo048204b

Reference yield:

: 108354-78-5
methyl 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate

: 309736-20-7
2-(2-formyl-1H-pyrrol-1-yl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / acetic acid / 4 h / Heating

2: 73 percent / POCl₃ / 5 h / 50 - 60 °C

3: 67 percent / KOH / H₂O; methanol / 3 h / Heating

With potassium hydroxide; acetic acid; trichlorophosphate; In methanol; water;
DOI:10.1021/jo048204b