4-Hydroxy-N,N-dipropylbenzenesulfonamide

Base Information

Chemical Name:4-Hydroxy-N,N-dipropylbenzenesulfonamide
CAS No.:30988-94-4
Molecular Formula:C12H19NO3S
Molecular Weight:257.354
Hs Code.:
DSSTox Substance ID:DTXSID301275744
Nikkaji Number:J1.629.342C

Synonyms:30988-94-4;DTXSID301275744;AKOS005870182;4-Hydroxy-N,N-dipropylbenzenesulfonamide

Suppliers and Price of 4-Hydroxy-N,N-dipropylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Hydroxy-N,N-dipropylbenzenesulfonamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:257.10856464
Heavy Atom Count:17
Complexity:296

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCN(CCC)S(=O)(=O)C1=CC=C(C=C1)O

Technology Process of 4-Hydroxy-N,N-dipropylbenzenesulfonamide

There total 5 articles about 4-Hydroxy-N,N-dipropylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: N,N-dipropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide

: 30988-94-4
4-hydroxy-N,N-dipropylbenzenesulfonamide

Guidance literature:: With tris(2,2’-bipyridyl)ruthenium(II) dichioride hexahydrate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Irradiation;
DOI:10.1021/acs.orglett.7b01950

Reference yield:

: C₁₇H₂₁NO₄S₂

: 30988-94-4
4-hydroxy-N,N-dipropylbenzenesulfonamide

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; methanol; at 40 ℃;
DOI:10.1002/anie.202108971

Reference yield:

: 57-66-9
4-[(dipropylamino)sulfonyl]benzoic acid

: 30988-94-4
4-hydroxy-N,N-dipropylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; dicyclohexyl-carbodiimide / 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran / 2 h / 20 °C / Schlenk technique; Inert atmosphere

2: isonicotinate tert-butyl ester / 15 h / 110 °C / Schlenk technique; Inert atmosphere; Sealed tube

3: tris(2,2’-bipyridyl)ruthenium(II) dichioride hexahydrate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C / Irradiation

With dmap; tris(2,2’-bipyridyl)ruthenium(II) dichioride hexahydrate; isonicotinate tert-butyl ester; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; N,N-dimethyl-formamide;
DOI:10.1021/acs.orglett.7b01950