Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate

Base Information

Chemical Name:Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate
CAS No.:31055-19-3
Molecular Formula:C₇H₉N₃O₃
Molecular Weight:183.167
Hs Code.:2933199050
European Community (EC) Number:641-606-0
UNII:S14QI5149O
DSSTox Substance ID:DTXSID10185014
Nikkaji Number:J928.312I
Wikidata:Q27288427
Mol file:31055-19-3.mol

Synonyms:31055-19-3;Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate;ethyl 5-formamido-1H-pyrazole-4-carboxylate;3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester;S14QI5149O;Pyrazole-4-carboxylic acid, 3-formamido-, ethyl ester;1H-Pyrazole-4-carboxylic acid, 3-(formylamino)-, ethyl ester;Allopurinol Impurity E;Allopurinol impurity E [EP];UNII-S14QI5149O;DTXSID10185014;VAEIHNPPOAVFAR-UHFFFAOYSA-N;3-formamido-4-ethoxycarbonylpyrazole;ALLOPURINOL IMPURITY E [EP IMPURITY];A899588;ETHYL 3-FORMAMIDO-1H-PYRAZOLE-4-CARBOXYLATE;Q27288427;3-Formamidopyrazole-4-carboxylic Acid Ethyl Ester;Allopurinol Imp. E (EP);Allopurinol USP Related Compound E;Allopurinol USP RC E;Ethyl 5-(Formylamino)-1H-pyrazole-4-carboxylate;Allopurinol Related Compound E

Suppliers and Price of Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Formylamino)-1H-pyrazole-4-carboxylicAcidEthylEster
1g
$ 1295.00

Sigma-Aldrich
Allopurinol Related Compound E United States Pharmacopeia (USP) Reference Standard
25mg
$ 1160.00

Sigma-Aldrich
Allopurinol impurity E European Pharmacopoeia (EP) Reference Standard
a0350050
$ 190.00

Sigma-Aldrich
Allopurinol Related Compound E Pharmaceutical Secondary Standard; Certified Reference Material
50mg
$ 482.00

Matrix Scientific
Ethyl 5-formamido-1H-pyrazole-4-carboxylate 95%
5g
$ 3664.00

Matrix Scientific
Ethyl 5-formamido-1H-pyrazole-4-carboxylate 95%
1g
$ 1814.00

Biosynth Carbosynth
Allopurinol impurity E
250 mg
$ 350.00

Biosynth Carbosynth
Allopurinol impurity E
100 mg
$ 182.00

Biosynth Carbosynth
Allopurinol impurity E
50 mg
$ 120.00

Biosynth Carbosynth
Allopurinol impurity E
25 mg
$ 78.00

Total 14 raw suppliers

Chemical Property of Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate

Chemical Property:

Melting Point:192.5-193.5 °C(Solv: ethanol (64-17-5))
Boiling Point:483.2±30.0 °C(Predicted)
PKA:10.18±0.50(Predicted)
PSA：87.57000
Density:1.385±0.06 g/cm3(Predicted)
LogP:0.80420
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:183.06439116
Heavy Atom Count:13
Complexity:197

Purity/Quality:

99%, ^*data from raw suppliers

3-(Formylamino)-1H-pyrazole-4-carboxylicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NN=C1)NC=O
Uses 3-(Formylamino)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (Allopurinol EP Impurity E) is an impurity of Allopurinol (A547300), a pyrazole derivative that has been shown to induce neoplasm immunogenicity.

Technology Process of Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate

There total 2 articles about Ethyl 5-(formylamino)-1H-pyrazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: