5H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-, ethyl ester

Base Information

• Chemical Name: 5H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-, ethyl ester
• CAS No.: 314042-00-7
• Molecular Formula: C20H22N2O4S2
• Molecular Weight: 418.53000
• Mol file: 314042-00-7.mol

Synonyms:2-(3-Benzoyl-thioureido)-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylic acid ethyl ester;2-(N'-benzoylthioureido)-3-carbethoxy-5,5-dimethyl-4,5-dihydro-7H-thieno[2,3-c]pyran;

Chemical Property of 5H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-, ethyl ester

Chemical Property:

• PSA: 136.99000
• LogP: 4.36680

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-, ethyl ester

There total 1 articles about 5H-Thieno[2,3-c]pyran-3-carboxylic acid, 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate (64792-51-4) + Benzoyl isothiocyanate (532-55-8) → 2-(N'-benzoylthioureido)-3-ethoxycarbonyl-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran (314042-00-7)

Guidance literature:

In methanol; for 3h;

DOI:10.1023/B:COHC.0000023772.87295.a9

Reference yield: 96.5%

2-(N'-benzoylthioureido)-3-ethoxycarbonyl-5,5-dimethyl-5,7-dihydro-4H-thieno[2,3-c]pyran (314042-00-7) → 6,6-dimethyl-2-thioxo-5,6-dihydro-8H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one (300730-47-6)

Guidance literature:

With potassium hydroxide; In ethanol; water; for 2h; Heating;

DOI:10.1023/A:1010445510155

upstream raw materials:

ethyl 2-amino-5,5-dimethyl-4,7-dihydro-5H-thieno[2,3-c]pyran-3-carboxylate

Benzoyl isothiocyanate

Downstream raw materials:

6,6-dimethyl-2-thioxo-5,6-dihydro-8H-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-one