1-(1-Phenyl-2-methylcyclohexyl)piperidine

Base Information

Chemical Name:1-(1-Phenyl-2-methylcyclohexyl)piperidine
CAS No.:59397-29-4
Molecular Formula:C₁₈H₂₇N
Molecular Weight:257.419
Hs Code.:
DSSTox Substance ID:DTXSID50974808
ChEMBL ID:CHEMBL424429
Mol file:59397-29-4.mol

Synonyms:1-(1-phenyl-2-methylcyclohexyl)piperidine;1-(1-phenyl-2-methylcyclohexyl)piperidine dihydrobromide, hydrate;1-(1-phenyl-2-methylcyclohexyl)piperidine dihydrobromide, hydrate, (-)-isomer;1-(1-phenyl-2-methylcyclohexyl)piperidine hydrochloride, (+-)-isomer;1-(1-phenyl-2-methylcyclohexyl)piperidine, (+)-isomer;1-(1-phenyl-2-methylcyclohexyl)piperidine, (-)-isomer;1-(1-phenyl-2-methylcyclohexyl)piperidine, (cis)-isomer;1-(1-phenyl-2-methylcyclohexyl)piperidine, (trans)-isomer;1-PMCPP

Suppliers and Price of 1-(1-Phenyl-2-methylcyclohexyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 21 raw suppliers

Chemical Property of 1-(1-Phenyl-2-methylcyclohexyl)piperidine

Chemical Property:

Vapor Pressure:4.7E-05mmHg at 25°C
Boiling Point:349.5°C at 760 mmHg
Flash Point:149.4°C
PSA：3.24000
Density:0.989g/cm³
LogP:4.51580
XLogP3:4.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:257.214349865
Heavy Atom Count:19
Complexity:275

Purity/Quality:: 99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CCCCC1(C2=CC=CC=C2)N3CCCCC3

Technology Process of 1-(1-Phenyl-2-methylcyclohexyl)piperidine

There total 3 articles about 1-(1-Phenyl-2-methylcyclohexyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 111-24-0
1,5-dibromo-pentane

: 125801-95-8
trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)amine hydrochloride

: 58283-43-5,58283-44-6,59397-29-4,134005-78-0,134005-89-3,134005-90-6,134053-32-0,134053-33-1
trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)piperidine

Guidance literature:: With potassium carbonate; potassium iodide; In ethanol; for 168h; Heating;
DOI:10.1021/jm00112a041

Reference yield:

: 15036-22-3
1-phenyl-2-methylcyclohexanol

: 58283-43-5,58283-44-6,59397-29-4,134005-78-0,134005-89-3,134005-90-6,134053-32-0,134053-33-1
trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)piperidine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide, concd. H₂SO₄ / CHCl₃ / 6 h / 0 °C

2: LAH / diethyl ether / 1 h / Heating

3: 80 percent / KI, K₂CO₃ / ethanol / 168 h / Heating

With lithium aluminium tetrahydride; sodium azide; sulfuric acid; potassium carbonate; potassium iodide; In diethyl ether; ethanol; chloroform;
DOI:10.1021/jm00112a041

Reference yield:

: 66021-72-5
(1-Azido-2-methyl-cyclohexyl)-benzene

: 58283-43-5,58283-44-6,59397-29-4,134005-78-0,134005-89-3,134005-90-6,134053-32-0,134053-33-1
trans-Ph/Me 1-(1-phenyl-2-methylcyclohexyl)piperidine

Guidance literature:: Multi-step reaction with 2 steps

1: LAH / diethyl ether / 1 h / Heating

2: 80 percent / KI, K₂CO₃ / ethanol / 168 h / Heating

With lithium aluminium tetrahydride; potassium carbonate; potassium iodide; In diethyl ether; ethanol;
DOI:10.1021/jm00112a041