2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone

Base Information

Chemical Name:2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone
CAS No.:3166-54-9
Molecular Formula:C16H13ClN2O
Molecular Weight:284.745
Hs Code.:
Mol file:3166-54-9.mol

Synonyms:2-chloromethyl-3-(2-methyl-phenyl)-3H-quinazolin-4-one;2-chloromethyl-3-o-tolyl-3H-quinazolin-4-one;2-chloromethyl-3-(o-tolyl)quinazolin-4-(3H)-one;2-chloromethyl-3-(2-methylphenyl)-3H-quinazolin-4-one;2-Chlormethyl-3-o-tolyl-3,4-dihydro-chinazolinon-(4);

Suppliers and Price of 2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(Chloromethyl)-3-(o-tolyl)quinazolin-4(3H)-one 97%
5g
$ 349.00

Chemenu
2-(Chloromethyl)-3-(o-tolyl)quinazolin-4(3H)-one 97%
5g
$ 329.00

Total 5 raw suppliers

Chemical Property of 2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone

Chemical Property:

Melting Point:205 - 206 °C
PSA：34.89000
LogP:3.43290

Purity/Quality:

99% ^*data from raw suppliers

2-(Chloromethyl)-3-(o-tolyl)quinazolin-4(3H)-one 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-(Chloromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one is used in biological studies to examine hypnotic activity.

Technology Process of 2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone

There total 4 articles about 2-(chloromethyl)-3-(2-methylphenyl)-4(3H)-quinazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 95-53-4
o-toluidine

: 14422-49-2
2-chloroacetamidobenzoic acid

: 3166-54-9
2-(chloromethyl)-3-(2-methylphenyl)-3H-quinazoline-4-one

Guidance literature:: With trichlorophosphate; In toluene; at 115 ℃;
DOI:10.1007/BF00905474

Reference yield: 29.0%

: 3166-54-9
2-(chloromethyl)-3-(2-methylphenyl)-3H-quinazoline-4-one

Guidance literature:

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 3166-54-9
2-(chloromethyl)-3-(2-methylphenyl)-3H-quinazoline-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C

2: pyridine / Reflux

With pyridine; triethylamine; In dichloromethane;
DOI:10.1080/00397910902735381