3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide

Base Information

• Chemical Name: 3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide
• CAS No.: 3192-06-1
• Molecular Formula: C8H9NO2S
• Molecular Weight: 183.231
• Hs Code.: 2934991000
• European Community (EC) Number: 893-820-0
• Nikkaji Number: J2.745.202G
• Mol file: 3192-06-1.mol

Synonyms:3192-06-1;3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide;1H-2,1-Benzothiazine, 3,4-dihydro-, 2,2-dioxide;3,4-dihydro-1H-2lambda6,1-benzothiazine-2,2-dione;3,4-dihydro-1H-2lambda6,1-benzothiazine 2,2-dioxide;SCHEMBL4558206;SFUUSVZJOLXBIB-UHFFFAOYSA-N;AKOS022970682;EN300-697272;3,4-dihydro-1H-2|E?,1-benzothiazine-2,2-dione;3,4-Dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide;Z1862025194

Chemical Property of 3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide

Chemical Property:

• PSA: 54.55000
• LogP: 2.20320
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 183.03539970
• Heavy Atom Count: 12
• Complexity: 255

Purity/Quality:

95% ^*data from raw suppliers

3,4-Dihydro-1H-2,1-benzothiazine2,2-dioxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CS(=O)(=O)NC2=CC=CC=C21

Technology Process of 3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide

There total 19 articles about 3,4-Dihydro-1H-2,1-benzothiazine 2,2-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-methoxy-3,4-dihydro-1H-2,1-benzothiazine 2,2-dioxide → 3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide (3192-06-1)

Guidance literature:

With samarium diiodide; In tetrahydrofuran;

DOI:10.1039/b301330h

Reference yield: 95.0%

1H-benzo[c][1,2]thiazine 2,2-dioxide (3192-05-0) → 3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide (3192-06-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 17h;

Reference yield: 95.0%

1-benzyl-3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide → 3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide (3192-06-1)

Guidance literature:

With Pd(OH)2/C; hydrogen; In ethanol; ethyl acetate; at 20 ℃; for 48h;

DOI:10.1055/s-0028-1216725

upstream raw materials:

tetradecane

β-phenethylsulfonyl azide

cyclohexane

benzene

Downstream raw materials:

1-phenyl-3,4-dihydro-1H-benzo[c][1,2]thiazine 2,2-dioxide

indole

1-indoline

Refernces

• 1、 Buckingham, Faye,Calderwood, Samuel,Checa, Bego?a,Keller, Thomas,Tredwell, Matthew,Collier, Thomas Lee,Newington, Ian M.,Bhalla, Rajiv,Glaser, Matthias,Gouverneur, Véronique. "Oxidative fluorination of N-arylsulfonamides". . p. 33 - 39. Retrieved 2015/09/22.
• 2、 Moroda, Atsushi,Furuyama, Shusuke,Togo, Hideo. "Facile preparation of 3,4-dihydro-2,1-benzothiazine 2,2-dioxides and related reaction with 1,3-diiodo-5,5-dimethylhydantoin under photochemical conditions". experimental part. p. 1336 - 1340. Retrieved 2009/11/30.