3-(2-Methoxyphenoxy)propan-1-amine

Base Information

• Chemical Name: 3-(2-Methoxyphenoxy)propan-1-amine
• CAS No.: 3245-88-3
• Molecular Formula: C10H15NO2
• Molecular Weight: 181.23200
• Hs Code.: 2922299090
• European Community (EC) Number: 679-397-3
• DSSTox Substance ID: DTXSID00389983
• Wikidata: Q72517452
• Mol file: 3245-88-3.mol

Synonyms:3245-88-3;3-(2-methoxyphenoxy)propan-1-amine;3-(2-Methoxyphenoxy)propylamine;3-(2-Methoxy-phenoxy)-propylamine;1-(3-aminopropoxy)-2-methoxybenzene;3-(2-METHOXYPHENOXY)PROPYLAMINE HCL;SCHEMBL6649844;DTXSID00389983;JGYVHBXLANTDMO-UHFFFAOYSA-N;3-(2-methoxyphenoxy)-1-Propanamine;MFCD05053657;3-(2-Methoxyphenoxyl)propan-1-amine;AKOS000140017;AS-40547;SY008297;BB 0221301;CS-0179158;FT-0677270;EN300-69499;A875611;J-510522;Z271006104

Chemical Property of 3-(2-Methoxyphenoxy)propan-1-amine

Chemical Property:

• Vapor Pressure: 0.00315mmHg at 25°C
• Boiling Point: 283.5oC at 760 mmHg
• PKA: 9.60±0.10(Predicted)
• Flash Point: 136oC
• PSA: 44.48000
• Density: 1.04g/cm3
• LogP: 2.12310
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 181.110278721
• Heavy Atom Count: 13
• Complexity: 130

Purity/Quality:

97% ^*data from raw suppliers

3-(2-Methoxyphenoxy)propylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=CC=C1OCCCN

Technology Process of 3-(2-Methoxyphenoxy)propan-1-amine

There total 3 articles about 3-(2-Methoxyphenoxy)propan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(o-methoxyphenoxy)propionitrile (70786-42-4) → 3-(2-methoxyphenoxy)propan-1-amine (3245-88-3)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid;

DOI:10.1021/jm00327a017

Reference yield:

N-[3-(2-methoxyphenoxy)propyl]phthalimide (3246-02-4) → 3-(2-methoxyphenoxy)propan-1-amine (3245-88-3)

Guidance literature:

Multistep reaction; (i) N₂H₄*H₂O, EtOH, (ii) aq. HCl;

DOI:10.1021/jm00327a017

Reference yield:

→ 3-(2-methoxyphenoxy)propan-1-amine (3245-88-3)

Guidance literature:

With hydrazine hydrate; In ethanol; for 20h; Reflux;

upstream raw materials:

N-[3-(2-methoxyphenoxy)propyl]phthalimide

3-(o-methoxyphenoxy)propionitrile

Downstream raw materials:

N-<2-(3-Methoxy-phenoxy)-ethyl>-3-(2-methoxy-phenoxy)-propylamin

2-(3,4-Dimethoxy-phenyl)-2-isopropyl-5-[3-(2-methoxy-phenoxy)-propylamino]-pentanenitrile

α-isopropyl-3,4,5-trimethoxy-α-<3-<<3-(2-methoxyphenoxy)propyl>amino>propyl>-benzeneacetonitrile

alpha-isopropyl-alpha-[2-[N-[3-(2-methoxyphenoxy)propyl]amino]ethyl]-3,4,5-trimethoxyphenylacetonitrile