3-trityl-1H-indole

Base Information

• Chemical Name: 3-trityl-1H-indole
• CAS No.: 32863-87-9
• Molecular Formula: C27H21N
• Molecular Weight: 359.47
• DSSTox Substance ID: DTXSID80454062
• Nikkaji Number: J550.386H
• Wikidata: Q82275392
• Mol file: 32863-87-9.mol

Synonyms:3-trityl-1H-indole;32863-87-9;3-(triphenylmethyl)-1H-indole;3-tritylindole;SCHEMBL7915295;DTXSID80454062;MFCD02173799;AKOS015959779;LS-05000

Chemical Property of 3-trityl-1H-indole

Chemical Property:

• XLogP3: 7.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 359.167399674
• Heavy Atom Count: 28
• Complexity: 435

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CNC5=CC=CC=C54

Technology Process of 3-trityl-1H-indole

There total 29 articles about 3-trityl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trityl perchlorate (16721-97-4) + 2-(indol-3-yl)-1-methyl-1,2-dihydroquinoline (90731-53-6) → (indol-3-yl)triphenylmethane (32863-87-9) + N-methylquinolinium perchlorate

Guidance literature:

In dichloromethane; acetonitrile; for 1h;

DOI:10.1007/BF00506395

Reference yield: 99.0%

indole (120-72-9) + triphenylmethyl alcohol (76-84-6) → (indol-3-yl)triphenylmethane (32863-87-9)

Guidance literature:

With pentafluorophenylboronic acid; In 1,2-dichloro-ethane; for 16h; Reflux; Molecular sieve;

DOI:10.1016/j.tetlet.2010.02.151

Reference yield: 89.0%

triphenylmethyl perchlorate + 2-cyclohexylsulfonyl-1-(3-indolyl)-1,2-dihydroisoquinoline (71905-89-0) → (indol-3-yl)triphenylmethane (32863-87-9) + 2-Cyclohexanesulfonyl-isoquinolinium; perchlorate

Guidance literature:

In acetonitrile;

DOI:10.1007/BF00471806

upstream raw materials:

indole

triphenylmethyl alcohol

triphenylmethane

1,4-diacetyl-2,3-di(indolyl-3)-1,2,3,4-tetrahydropyrazine