Diethyl 4-cyano-2-fluorobenzylphosphonate

Base Information

Chemical Name:Diethyl 4-cyano-2-fluorobenzylphosphonate
CAS No.:329744-58-3
Molecular Formula:C₁₂H₁₅FNO₃P
Molecular Weight:271.228
Hs Code.:
DSSTox Substance ID:DTXSID40450186
Nikkaji Number:J1.614.910A
Wikidata:Q82269785

Synonyms:Diethyl 4-cyano-2-fluorobenzylphosphonate;329744-58-3;SCHEMBL4680035;DTXSID40450186;XATVBVSZUHEWET-UHFFFAOYSA-N;Diethyl 4-cyano-2-flourobenzylphosphonate;SY309553;diethyl 4-cyano-2-fluorobenzyl-phosphonate;3-Fluoro-4-(diethoxyphosphinylmethyl)benzonitrile

Suppliers and Price of Diethyl 4-cyano-2-fluorobenzylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Diethyl 4-cyano-2-fluorobenzylphosphonate

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:271.07735850
Heavy Atom Count:18
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(CC1=C(C=C(C=C1)C#N)F)OCC

Technology Process of Diethyl 4-cyano-2-fluorobenzylphosphonate

There total 3 articles about Diethyl 4-cyano-2-fluorobenzylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 170572-49-3
2-fluoro-4-cyanotoluene

: 329744-58-3
diethyl 4-cyano-2-fluorobenzylphosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: 63 percent / N-bromosuccinimide; 2,2'-azobis(isobutyronitrile) / 1,2-dichloro-ethane / 0.42 h / Irradiation

2: 2 h / 150 °C

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In 1,2-dichloro-ethane;
DOI:10.1248/cpb.49.1647