1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE

Base Information

• Chemical Name: 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE
• CAS No.: 332023-12-8
• Molecular Formula: C10H12ClN3O2
• Molecular Weight: 241.677
• Hs Code.: 2933599590
• Mol file: 332023-12-8.mol

Synonyms:BUTTPARK 839-96;1-(2-chloro-6-nitro-phenyl)-piperazine;3-Chloro-2-(piperazin-1-yl)nitrobenzene;1-(2-chloro-6-nitrophenyl)piperazine(SALTDATA: FREE);AKOS BB-8576;

Chemical Property of 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE

Chemical Property:

• Vapor Pressure: 4.14E-06mmHg at 25°C
• Melting Point: 95-97oC
• Boiling Point: 384.3oC at 760 mmHg
• PKA: 8.60±0.10(Predicted)
• Flash Point: 186.2oC
• PSA: 61.09000
• Density: 1.331g/cm3
• LogP: 2.57480

Purity/Quality:

99%, ^*data from raw suppliers

1-(2-Chloro-6-nitrophenyl)piperazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE

There total 3 articles about 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-(2-chloro-6-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (400803-05-6) → 1-(2-chloro-6-nitro-phenyl)-piperazine (332023-12-8)

Guidance literature:

In dichloromethane; trifluoroacetic acid;

Reference yield:

piperazine (110-85-0) + 1,2-Dichloro-3-nitrobenzene (3209-22-1) → 1-(2-chloro-6-nitro-phenyl)-piperazine (332023-12-8)

Guidance literature:

In neat; at 180 ℃;

DOI:10.1016/j.bmcl.2009.03.086

Reference yield:

1,2-Dichloro-3-nitrobenzene (3209-22-1) → 1-(2-chloro-6-nitro-phenyl)-piperazine (332023-12-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile

2: dichloromethane; trifluoroacetic acid

With potassium carbonate; In dichloromethane; acetonitrile; trifluoroacetic acid;

upstream raw materials:

4-(2-chloro-6-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

piperazine

1,2-Dichloro-3-nitrobenzene

Downstream raw materials:

1-{3-[4-(2-chloro-6-nitro-phenyl)-piperazin-1-yl]-propyl}-5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine

4-(2-chloro-6-nitro-phenyl)-piperazine-1-carboxylic acid tert-butyl ester

3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenylamine

1-[3-chloro-2-(4-{3-[5-methanesulfonyl-3-(4-trifluoromethyl-phenyl)-4,5,6,7-tetrahydro-pyrazolo[4,3-c]pyridin-1-yl]-propyl}-piperazin-1-yl)-phenyl]-urea

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 332023-12-8 1-(2-CHLORO-6-NITROPHENYL)PIPERAZINE

Send

Send

Metric Ton KG G Pound L ML

Send

Send