(Diphenylphosphoryl)(phenyl)methanone

Base Information

• Chemical Name: (Diphenylphosphoryl)(phenyl)methanone
• CAS No.: 33327-41-2
• Molecular Formula: C19H15O2P
• Molecular Weight: 306.301
• DSSTox Substance ID: DTXSID00500378
• Nikkaji Number: J1.691.039B
• Wikidata: Q82351925
• Mol file: 33327-41-2.mol

Synonyms:(Diphenylphosphoryl)(phenyl)methanone;33327-41-2;SCHEMBL58814;benzoyldiphenyl phosphine oxide;DTXSID00500378

Chemical Property of (Diphenylphosphoryl)(phenyl)methanone

Chemical Property:

• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 306.08096671
• Heavy Atom Count: 22
• Complexity: 391

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)P(=O)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of (Diphenylphosphoryl)(phenyl)methanone

There total 9 articles about (Diphenylphosphoryl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-Oxo-phenylmethan-diphenylphosphin (36838-04-7) → diphenyl(benzoyl)phosphine oxide (33327-41-2)

Guidance literature:

With tert.-butylhydroperoxide; vanadia; In chlorobenzene; at 40 ℃; for 0.00277778h; under 1500.15 Torr;

Reference yield:

(diphenylphosphinoyl)(phenyl)methanol (20684-82-6) → diphenyl(benzoyl)phosphine oxide (33327-41-2)

Guidance literature:

With manganese(IV) oxide; at 20 ℃; Darkness;

DOI:10.1016/j.jphotochem.2021.113517

Reference yield:

Diphenylphosphine oxide (4559-70-0) → diphenyl(benzoyl)phosphine oxide (33327-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 25 °C / Schlenk technique; Inert atmosphere

2: 25 °C / Schlenk technique; Inert atmosphere

With triethylamine; In tetrahydrofuran;

DOI:10.1021/acs.orglett.0c01384

upstream raw materials:

α-Oxo-phenylmethan-diphenylphosphin

benzaldehyde

chloro-diphenylphosphine

Diphenylphosphine oxide