N-benzyl-2-bromo-5-methoxybenzamide

Base Information

Chemical Name:N-benzyl-2-bromo-5-methoxybenzamide
CAS No.:336129-03-4
Molecular Formula:C15H14BrNO2
Molecular Weight:320.186
Hs Code.:
DSSTox Substance ID:DTXSID20368972
Nikkaji Number:J1.775.912D
Wikidata:Q82155894

Synonyms:N-benzyl-2-bromo-5-methoxybenzamide;336129-03-4;Benzamide, 2-bromo-5-methoxy-N-(phenylmethyl)-;DTXSID20368972;AKOS008462908;A1-05011

Suppliers and Price of N-benzyl-2-bromo-5-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
N-Benzyl-2-bromo-5-methoxybenzamide 95%
5g
$ 1320.00

A1 Biochem Labs
N-benzyl-2-bromo-5-methoxybenzamide 95%
5 g
$ 800.00

Total 0 raw suppliers

Chemical Property of N-benzyl-2-bromo-5-methoxybenzamide

Chemical Property:

PSA：41.82000
LogP:3.96250
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:319.02079
Heavy Atom Count:19
Complexity:292

Purity/Quality:: N-Benzyl-2-bromo-5-methoxybenzamide 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)Br)C(=O)NCC2=CC=CC=C2

Technology Process of N-benzyl-2-bromo-5-methoxybenzamide

There total 4 articles about N-benzyl-2-bromo-5-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 22921-68-2
2-bromo-5-methoxy-benzoic acid

: 100-46-9
benzylamine

: 336129-03-4
N-benzyl 2-bromo-5-methoxybenzamide

Guidance literature:: With dmap; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 0 - 12 ℃; for 12h;
DOI:10.1016/j.mcat.2021.111766

Reference yield:

: 56658-04-9
2-bromo-5-methoxybenzoyl chloride

: 100-46-9
benzylamine

: 336129-03-4
N-benzyl 2-bromo-5-methoxybenzamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/ol062599z

Reference yield:

: 22921-68-2
2-bromo-5-methoxy-benzoic acid

: 336129-03-4
N-benzyl 2-bromo-5-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / toluene; dimethylformamide / 0 - 70 °C

2: 246 mg / triethylamine / CH₂Cl₂ / 0 - 20 °C

With thionyl chloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ol062599z