Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride

Base Information

Chemical Name:Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride
CAS No.:131448-15-2
Molecular Formula:C23H29ClN4O4
Molecular Weight:460.9538
Hs Code.:
DSSTox Substance ID:DTXSID50157053

Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride

Synonyms:131448-15-2;Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride;DTXSID50157053;LS-134104

Suppliers and Price of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride

Chemical Property:

Vapor Pressure:1.22E-13mmHg at 25°C
Boiling Point:584.4°Cat760mmHg
Flash Point:307.2°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:460.1877331
Heavy Atom Count:32
Complexity:648

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CCN1C2=NC(=CC(=C2C(=O)N(C1=O)C3=CC=CC=C3)C(=O)OCC)C.Cl

Technology Process of Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride

There total 4 articles about Pyrido(2,3-d)pyrimidine-5-carboxylic acid, 1,2,3,4-tetrahydro-1-(2-(diethylamino)ethyl)-2,4-dioxo-7-methyl-3-phenyl-, ethyl ester, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 131448-12-9
ethyl 1(β-diethylaminoethyl)-3-phenyl-7-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido<2,3-d>pyrimidine-5-carboxylate

: 131448-15-2
1-(2-Diethylamino-ethyl)-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester; hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol;

Reference yield:

: 103-71-9
phenyl isocyanate

: 131448-15-2
1-(2-Diethylamino-ethyl)-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) NaOC₂H₅ / 1.) 45 min, 60 deg C 2.) benzene, EtOH, 2 h, reflux

2: 88 percent / NaOC₂H₅ / 20 h / Heating; 1.) ethanol 2.) benzene

3: 90 percent / HCl gas / ethanol

With hydrogenchloride; sodium ethanolate; In ethanol;

Reference yield:

: 91558-58-6
diethyl 2-amino-6-methylpyridine-3,4-dicarboxylate

: 131448-15-2
1-(2-Diethylamino-ethyl)-7-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydro-pyrido[2,3-d]pyrimidine-5-carboxylic acid ethyl ester; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) NaOC₂H₅ / 1.) 45 min, 60 deg C 2.) benzene, EtOH, 2 h, reflux

2: 88 percent / NaOC₂H₅ / 20 h / Heating; 1.) ethanol 2.) benzene

3: 90 percent / HCl gas / ethanol

With hydrogenchloride; sodium ethanolate; In ethanol;