Benzoic acid, 5-amino-2-[(4-aminophenyl)sulfonyl]-, methyl ester

Base Information

• Chemical Name: Benzoic acid, 5-amino-2-[(4-aminophenyl)sulfonyl]-, methyl ester
• CAS No.: 34332-21-3
• Molecular Formula: C14H14N2O4S
• Molecular Weight: 306.33700
• Mol file: 34332-21-3.mol

Synonyms:4,4'-diamino-2-methoxycarbonyl-diphenylsulfone;2-Carbomethoxy-4,4'-diaminodiphenyl sulfone;

Chemical Property of Benzoic acid, 5-amino-2-[(4-aminophenyl)sulfonyl]-, methyl ester

Chemical Property:

• PSA: 120.86000
• LogP: 3.71360

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 5-amino-2-[(4-aminophenyl)sulfonyl]-, methyl ester

There total 3 articles about Benzoic acid, 5-amino-2-[(4-aminophenyl)sulfonyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Acetamidophenyl-2-carboxymethoxy-4-nitrophenylsulfon (35880-92-3) → 4,4'-diamino-2-methoxycarbonyl-diphenylsulfone (34332-21-3)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / Raney-Ni

2: aq. HCl

With hydrogenchloride; hydrogen; nickel;

DOI:10.1021/jm00294a006

Reference yield:

sodium 4-acetamidobenzenesulfinate (15898-43-8) → 4,4'-diamino-2-methoxycarbonyl-diphenylsulfone (34332-21-3)

Guidance literature:

Multi-step reaction with 3 steps

2: H₂ / Raney-Ni

3: aq. HCl

With hydrogenchloride; hydrogen; nickel;

DOI:10.1021/jm00294a006

Reference yield:

4'-acetamino-4-amino-2-methoxycarbonyl-diphenylsulfone (35880-93-4) → 4,4'-diamino-2-methoxycarbonyl-diphenylsulfone (34332-21-3)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jm00294a006

upstream raw materials:

4'-acetamino-4-amino-2-methoxycarbonyl-diphenylsulfone

4-Acetamidophenyl-2-carboxymethoxy-4-nitrophenylsulfon

sodium 4-acetamidobenzenesulfinate

Downstream raw materials:

5-Amino-2-(4-amino-benzenesulfonyl)-benzoyl chloride

2-cyano-4,4'-diamino-diphenylsulfone

5-amino-2-sulfanilyl-benzoic acid amide

5-amino-2-sulfanilyl-benzoic acid