3-CHLORO-2-METHYLBENZENESULFONAMIDE

Base Information

• Chemical Name: 3-CHLORO-2-METHYLBENZENESULFONAMIDE
• CAS No.: 3476-03-7
• Molecular Formula: C7H8ClNO2S
• Molecular Weight: 205.665
• Hs Code.: 2935009090
• Mol file: 3476-03-7.mol

Synonyms:6-chloro-1,1-dioxothiochroman-4-one;3-chloro-2-methyl-benzene sulfonamide;3-chloro-2-methylbenzenesulphonamide;3-Chlor-2-methylbenzolsulfonamid;6-chlorothiochromanone-S,S-dioxide;6-chloro-toluene-2-sulfonic acid amide;6-Chlor-toluol-2-sulfonsaeure-amid;6-Chloro-1-benzothiopyran-4-one1,1-dioxide;6-chloro-2,3-dihydro-4H-thiochromen-4-one 1,1-dioxide;

Chemical Property of 3-CHLORO-2-METHYLBENZENESULFONAMIDE

Chemical Property:

• Melting Point: 181-183°C
• Boiling Point: 369.6±52.0 °C(Predicted)
• PKA: 9.90±0.60(Predicted)
• PSA: 68.54000
• Density: 1.402±0.06 g/cm3(Predicted)
• LogP: 3.07690

Purity/Quality:

98%Min ^*data from raw suppliers

3-Chloro-2-methylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

Useful:

Technology Process of 3-CHLORO-2-METHYLBENZENESULFONAMIDE

There total 1 articles about 3-CHLORO-2-METHYLBENZENESULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-chloro-N-isopropyl-2-methyl-benzenesulfonamide → 3-chloro-2-methylbenzenesulfonamide (3476-03-7)

Guidance literature:

With chromium(III) acetate hydroxide; periodic acid; In acetonitrile; at 20 ℃; for 18h;

DOI:10.1055/s-2004-830851

Reference yield: 83.0%

3-chloro-2-methylbenzenesulfonamide (3476-03-7) → 2-chloro-6-sulfamoylbenzoic acid (1242052-15-8)

Guidance literature:

3-chloro-2-methylbenzenesulfonamide; With potassium permanganate; sodium carbonate; In water; at 100 ℃;

In water; at 20 ℃; pH=1; Acidic conditions;

Reference yield: 80.0%

3-chloro-2-methylbenzenesulfonamide (3476-03-7) + acetic anhydride (108-24-7) → N-((3-chloro-2-methylphenyl)sulfonyl)acetamide

Guidance literature:

With zinc(II) chloride; at 50 ℃;

DOI:10.1021/jo502224d

Downstream raw materials:

3-chloro-2-methyl-N-(2-methylbenzothiazol-5-ylmethyl)benzenesulphonamide

3-chloro-2-methyl-N,N-bis(2-methylbenzothiazol-5-ylmethyl)benzenesulphonamide

2-chloro-6-sulfamoylbenzoic acid

C₂₁H₂₀Cl₂N₄O₂S

Refernces