4-Bromophenyl 2-hydroxyquinoline-4-carboxylate

Base Information

Chemical Name:4-Bromophenyl 2-hydroxyquinoline-4-carboxylate
CAS No.:355153-30-9
Molecular Formula:C₁₆H₁₀BrNO₃
Molecular Weight:344.164
Hs Code.:
DSSTox Substance ID:DTXSID70358580
Wikidata:Q82139239
Mol file:355153-30-9.mol

Synonyms:4-bromophenyl 2-hydroxyquinoline-4-carboxylate;355153-30-9;(4-bromophenyl) 2-oxo-1H-quinoline-4-carboxylate;Oprea1_240246;DTXSID70358580;STK379614;AKOS005449354;4-bromophenyl 2-hydroxy-4-quinolinecarboxylate;AK-918/14110006

Suppliers and Price of 4-Bromophenyl 2-hydroxyquinoline-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 4-Bromophenyl 2-hydroxyquinoline-4-carboxylate

Chemical Property:

PSA：59.42000
LogP:3.92210
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:342.98441
Heavy Atom Count:21
Complexity:454

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC(=O)N2)C(=O)OC3=CC=C(C=C3)Br

Technology Process of 4-Bromophenyl 2-hydroxyquinoline-4-carboxylate

There total 3 articles about 4-Bromophenyl 2-hydroxyquinoline-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 356084-48-5
2-chloro-quinoline-4-carboxylic acid 4-bromo-phenyl ester

: 355153-30-9
2-oxo-1,2-dihydro-quinoline-4-carboxylic acid 4-bromo-phenyl ester

Guidance literature:: With sodium acetate; In acetic acid; for 1h; Heating;
DOI:10.1023/A:1021258510259

Reference yield:

: 2388-32-1
2-chloroquinoline-4-carbonyl chloride

: 355153-30-9
2-oxo-1,2-dihydro-quinoline-4-carboxylic acid 4-bromo-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / benzene / 1 h / Heating

2: 91 percent / CH₃COONa / acetic acid / 1 h / Heating

With sodium acetate; triethylamine; In acetic acid; benzene;
DOI:10.1023/A:1021258510259

Reference yield:

: 5467-57-2
2-chloroquinoline-4-carboxylic acid

: 355153-30-9
2-oxo-1,2-dihydro-quinoline-4-carboxylic acid 4-bromo-phenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: thionyl chloride / 1 h / Heating

2: triethylamine / benzene / 1 h / Heating

3: 91 percent / CH₃COONa / acetic acid / 1 h / Heating

With thionyl chloride; sodium acetate; triethylamine; In acetic acid; benzene;
DOI:10.1023/A:1021258510259