Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane

Base Information

• Chemical Name: Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane
• CAS No.: 356056-14-9
• Molecular Formula: C14H19F13Si
• Molecular Weight: 462.36500
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID50583338
• Wikidata: Q82474901
• Mol file: 356056-14-9.mol

Synonyms:Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane, >=95%;Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane;VIGKXSZWCIUYJE-UHFFFAOYSA-N;NS00110562

Chemical Property of Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane

Chemical Property:

• Vapor Pressure: 0.0346mmHg at 25°C
• Boiling Point: 250.3oC at 760 mmHg
• Flash Point: 105.2oC
• PSA: 0.00000
• LogP: 7.16240
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 9
• Exact Mass: 462.1048432
• Heavy Atom Count: 28
• Complexity: 514

Purity/Quality:

98%,99%, ^*data from raw suppliers

DIISOPROPYL(3,3,4,4,5,5,6,6,7,7,8,8,8-TRIDECAFLUOROOCTYL)SILANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)[SiH](CCC(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)C(C)C

Technology Process of Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane

There total 2 articles about Diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane (2043-57-4,71215-70-8) + chlorodiisopropylsilane (2227-29-4) → diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane (356056-14-9)

Guidance literature:

1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane; With tert.-butyl lithium; In pentane; at -78 - -15 ℃;

chlorodiisopropylsilane; In pentane; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ja025606x

Reference yield:

→ diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane (356056-14-9)

Guidance literature:

Reference yield: 90.0%

(S)-1-(tert-butyldimethylsilyloxy)-4-(1-phenyl-1H-tetrazol-5-ylthio)butan-2-ol (1227373-83-2) + diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane (356056-14-9) → (S)-5-(4-(tert-butyldimethylsilyloxy)-3-(diisopropyl(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silyloxy)butylthio)-1-phenyl-1H-tetrazole (1227373-85-4)

Guidance literature:

diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silane; With trifluorormethanesulfonic acid; at 0 - 20 ℃; Inert atmosphere;

(S)-1-(tert-butyldimethylsilyloxy)-4-(1-phenyl-1H-tetrazol-5-ylthio)butan-2-ol; With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 4h; Inert atmosphere;

DOI:10.1055/s-0029-1219376

upstream raw materials:

1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane

chlorodiisopropylsilane

Downstream raw materials:

(4R)-4-benzyl-3-{(2R,3S)-5-tert-butyldimethylsilyloxy-3-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silyloxy]-2-methylpentanoyl}-1,3-oxazolidin-2-one

(S)-4-Benzyl-3-{(R)-2-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl)-silanyloxymethyl]-butyryl}-oxazolidin-2-one

3-{6-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silanyloxymethyl]-4-methyl-octa-2E,4E-dienoyl}-4-hydroxy-5-[4-(2-methoxyethoxymethoxy)phenyl]-1H-pyridine-2-one

(4E,6E)-8-[diisopropyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)silanyloxymethyl]-3-hydroxy-2-{2-[4-(2-methoxyethoxymethoxy)phenyl]vinylcarbamoyl}-6-methyl-deca-2,4,6-trienoic acid ethyl ester

Refernces

• 1、 Zhang, Qisheng,Rivkin, Alexey,Curran, Dennis P.. "Quasiracemic synthesis: Concepts and implementation with a fluorous tagging strategy to make both enantiomers of pyridovericin and mappicine". . p. 5774 - 5781. Retrieved 2007/10/03.