Arzoxifene hydrochloride

Base Information

• Chemical Name: Arzoxifene hydrochloride
• CAS No.: 182133-27-3
• Molecular Formula: C28H29 N O4 S . Cl H
• Molecular Weight: 512.067
• NSC Number: 714373
• UNII: FU88PI0433
• DSSTox Substance ID: DTXSID40939527
• Wikidata: Q27278209
• NCI Thesaurus Code: C2460
• ChEMBL ID: CHEMBL2105949
• Mol file: 182133-27-3.mol

Synonyms:Arzoxifene hydrochloride;Arzoxifene HCl;182133-27-3;SERM 3;Arzoxifene (hydrochloride);Arzoxifene hydrochloride [USAN];LY353381.HCl;LY 353381 HCl;LY-353381.HCl;SERM-3;UNII-FU88PI0433;182133-27-3 (HCl);FU88PI0433;2-(4-Methoxyphenyl)-3-(4-(2-(1-piperidinyl)ethoxy)phenoxy)benzo(b)thiophene-6-ol hydrochloride;2-(p-Methoxyphenyl)-3-(p-(2-(1-piperidinyl)ethoxy)phenoxy)benzo(b)thiophene-6-ol hydrochloride;2-(p-Methoxyphenyl)-3-(p-(2-piperidinoethoxy)phenoxy)benzo(b)thiophene-6-ol hydrochloride;Arzoxifene hydrochloride (USAN);2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol , hydrochloride;Benzo(b)thiophene-6-ol, 2-(4-methoxyphenyl)-3-(4-(2-(1-piperidinyl)ethoxy)phenoxy)-, hydrochloride;ArzoxifeneHCl;C28H29NO4S.ClH;SCHEMBL699600;CHEMBL2105949;DTXSID40939527;BCP20959;C28-H29-N-O4-S.Cl-H;ARZOXIFENE HYDROCHLORIDE [MI];HY-13556A;NSC714373;AKOS032947294;NSC-714373;SB19714;ARZOXIFENE HYDROCHLORIDE [MART.];ARZOXIFENE HYDROCHLORIDE [WHO-DD];MS-29507;LS-182452;LY 353381 HCl concept CR-98-023;CS-0007166;D02993;Q27278209;LY353381;LY-353381;LY 353381;2-(4-methoxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)phenoxy]-1-benzothiophen-6-ol;hydrochloride;2-(4-Methoxyphenyl)-3-{4-[2-(piperidin-1-yl)ethoxy]phenoxy}-1-benzothiophene-6-ol--hydrogen chloride (1/1)

Chemical Property of Arzoxifene hydrochloride

Chemical Property:

• Vapor Pressure: 7.85E-18mmHg at 25°C
• Melting Point: 156-160°
• Boiling Point: 656.4°Cat760mmHg
• Flash Point: 350.8°C
• PSA: 79.40000
• Density: g/cm³
• LogP: 7.67940
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 8
• Exact Mass: 511.1584073
• Heavy Atom Count: 35
• Complexity: 601

Purity/Quality:

99% ^*data from raw suppliers

2-(4-METHOXYPHENYL)-3-[4-[2-(PIPERIDIN-1-YL)ETHOXY]PHENOXY]-1-BENZOTHIOPHEN-6-OL HCL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=C(C3=C(S2)C=C(C=C3)O)OC4=CC=C(C=C4)OCCN5CCCCC5.Cl
• Recent ClinicalTrials: Tamoxifen Compared With LY353381 in Treating Women With Newly Diagnosed Breast Cancer
• Recent EU Clinical Trials: Efectos del Arzoxifeno en la incidencia de fracturas vertebrales y en la incidencia de cáncer de mama invasivo en las mujeres posmenopáusicas con osteoporosis o con baja densidad ósea
• Uses: Treatment of symptoms associated with uterine fibroids, endometriosis, and dysfunctional uterine bleeding; in the treatment of estrogen receptor positive recurrent/metastatic breast cancer; as an adjuvant to breast cancer therapy (selective estrogen recep.