3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl-

Base Information

• Chemical Name: 3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl-
• CAS No.: 3617-20-7
• Molecular Formula: C11H12N2O
• Molecular Weight: 188.229
• DSSTox Substance ID: DTXSID50357112
• Nikkaji Number: J1.581.553A
• Wikidata: Q82136855
• Mol file: 3617-20-7.mol

Synonyms:3617-20-7;3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl-;SCHEMBL10284043;DTXSID50357112;2-Methyl-6-phenyl-4,5-dihydropyridazine-3(2H)-one

Chemical Property of 3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl-

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 188.094963011
• Heavy Atom Count: 14
• Complexity: 254

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C(=O)CCC(=N1)C2=CC=CC=C2

Technology Process of 3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl-

There total 9 articles about 3(2H)-Pyridazinone, 4,5-dihydro-2-methyl-6-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C11H11ClN2O (1444832-64-7) → 6-oxo-1-methyl-3-phenyl-1,4,5,6-tetrahydropyridazine (3617-20-7)

Guidance literature:

With pyridine; oxygen; copper diacetate; sodium carbonate; In toluene; at 100 ℃; for 12h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/adsc.201300026

Reference yield: 86.0%

C11H11BrN2O (1444833-42-4) → 6-oxo-1-methyl-3-phenyl-1,4,5,6-tetrahydropyridazine (3617-20-7)

Guidance literature:

With pyridine; oxygen; copper diacetate; sodium carbonate; In toluene; at 100 ℃; for 12h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/adsc.201300026

Reference yield: 84.0%

C11H14N2O2 (1028250-15-8) → 6-oxo-1-methyl-3-phenyl-1,4,5,6-tetrahydropyridazine (3617-20-7)

Guidance literature:

at 140 - 150 ℃;

DOI:10.1515/HC.2007.13.2-3.161

upstream raw materials:

2-methyl-6-phenylpyridazin-3(2H)-one

C₁₁H₁₄N₂O₂

succinylbenzene

C₁₁H₁₁ClN₂O

Downstream raw materials:

2-Methyl-3,3,6,6-tetraphenylhexahydropyridazine

2-methyl-6-phenylpyridazin-3(2H)-one